Levofloxacin Krka

Levofloxacin Krka is an antibiotic that helps to kill bacteria causing various infections in your body.

Form
tabletti, kalvopäällysteinen
Strength
250 mg
Active Ingredient
Levofloxacin hemihydrate
Manufacturer
KRKA d.d. Novo mesto

How to Use

Dosage

Your doctor will decide your dose, usually one or two 250 mg tablets once daily or one 500 mg tablet once or twice daily, depending on your infection.

Method

Swallow the tablets whole with water. You can take them with or without food. The tablet can be divided into equal doses.

Important

Your doctor will determine the maximum daily dose, which is usually up to 1000 mg.

Possible Side Effects

COMMON
  • Sleep problems
  • Headache, dizziness
  • Nausea, vomiting and diarrhea
  • Increase in certain blood liver enzyme levels
RARE
  • Allergic reaction (rash, difficulty swallowing or breathing, swelling of lips, face, throat, or tongue)
  • Bloody diarrhea with stomach cramps and high fever (signs of severe bowel problems)
  • Tendon or ligament pain and inflammation, possibly leading to rupture (often in the Achilles tendon)
  • Seizures
  • Seeing or hearing things that are not real (hallucinations, paranoia)
  • Feeling depressed, mental health problems, restlessness (agitation), abnormal dreams or nightmares
  • Widespread rash, fever, elevated liver enzymes, abnormal blood counts (eosinophilia), enlarged lymph nodes, and effects on other organs (DRESS syndrome)
  • Syndrome with reduced urine excretion and low blood sodium levels (SIADH)
  • Low blood sugar (hypoglycemia) or low blood sugar leading to coma (hypoglycemic coma), important for diabetics
  • Burning, tingling pain or numbness (signs of peripheral nerve damage/neuropathy)
  • Changes in the number of other bacteria or fungi, Candida yeast infection that may require treatment
  • Changes in white blood cell counts seen in blood tests (leukopenia, eosinophilia)
  • Anxiety, confusion, nervousness, drowsiness, tremor, spinning sensation (vertigo)
  • Shortness of breath
  • Taste changes, loss of appetite, stomach problems or indigestion, stomach pain, bloating (flatulence) or constipation
  • Itching and rash, severe itching or hives (urticaria), excessive sweating
  • Joint or muscle pain
  • Abnormal blood test results due to liver (increased bilirubin) or kidney (increased creatinine) problems
  • General weakness
  • Bruising or easy bleeding due to decreased blood platelets (thrombocytopenia)
  • Low white blood cell count (neutropenia)
  • Overactive immune system (hypersensitivity)
  • Hearing problems (tinnitus) or vision problems (blurred vision)
  • Unusually fast heartbeat (tachycardia) or low blood pressure (hypotension)
  • Muscle weakness (important for people with myasthenia gravis)
  • Memory impairment
  • Changes in kidney function and temporary kidney failure
  • Fever
  • Clearly defined, red spots with or without blisters on skin or mucous membranes, often recurring in the same spot if taken again
  • Severe skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis (red target-like spots or round patches with blisters, peeling skin, sores in mouth/throat/nose/genitals/eyes, fever, flu-like symptoms)
  • Loss of appetite, yellowing of skin and whites of eyes (jaundice), dark urine, itching, or tender stomach (signs of liver problems, possibly leading to fatal liver failure)
  • Changes in mood and thoughts (psychotic reactions), with risk of suicidal thoughts or attempts
  • Nausea, general unwellness, stomach discomfort/pain, or vomiting (signs of acute pancreatitis)
  • Reduction in red blood cells (anemia), which can cause pale skin or yellowness, due to destruction of red blood cells
  • Reduction in all blood cells (pancytopenia), bone marrow failure leading to fatigue, reduced infection resistance, and uncontrolled bleeding
  • Fever, sore throat, and general malaise that doesn't improve (due to very low white blood cell count - agranulocytosis)
  • Loss of circulation (anaphylactic shock)
  • Fluctuations in blood sugar (hyperglycemia or hypoglycemia), potentially leading to coma, important for diabetics
  • Changes in sense of smell, loss of smell or taste
  • Strong feelings of excitement, joy, restlessness, or enthusiasm (mania)
  • Problems moving or walking (dyskinesia, extrapyramidal disorders)
  • Fainting
  • Temporary vision loss, eye inflammation
  • Hearing impairment or loss
  • Abnormally fast heartbeat, life-threatening irregular heartbeat, including cardiac arrest, changes in heart rhythm (prolonged QT interval on ECG)
  • Difficulty breathing or wheezing (bronchospasm)
  • Allergic lung reactions
  • Pancreatitis
  • Liver inflammation (hepatitis)
  • Increased skin sensitivity to sun and UV light, darker skin areas (hyperpigmentation)
  • Inflammation of blood vessels due to allergic reaction (vasculitis)
  • Mouth inflammation
  • Muscle ruptures and muscle wasting (rhabdomyolysis)
  • Joint redness and swelling (arthritis)
  • Pain, including back, chest, and limb pain
  • Sudden involuntary jerking, muscle twitching, or muscle spasms (myoclonus)
  • Porphyria attacks in people with porphyria (a very rare metabolic disease)
  • Persistent headache with or without blurred vision (benign intracranial hypertension)

Important Warnings

  • Do not take if you are allergic to levofloxacin, other quinolone antibiotics, or any other ingredients of this medicine. Signs of an allergic reaction include rash, trouble swallowing or breathing, and swelling of your lips, face, throat, or tongue.
  • This medicine should not be given to children or growing adolescents.
  • Do not take this medicine if you are pregnant, planning to become pregnant, or breastfeeding.
  • Stop taking this medicine and see a doctor immediately if you develop a severe rash or other skin symptoms.
  • If you feel sudden severe pain in your stomach, chest, or back, go to an emergency room immediately, as these could be signs of an aortic aneurysm or dissection.
Show 10 more warnings
  • Contact a doctor immediately if you experience sudden shortness of breath, especially when lying down, or swelling in your ankles, feet, or abdomen, or new heart palpitations.
  • See a doctor immediately if you experience sudden involuntary jerking, muscle twitching, or muscle spasms, as this could be a sign of myoclonus.
  • Go to a doctor immediately if you have nausea, general unwellness, severe stomach problems, constant or worsening stomach pain, or vomiting, as these could be signs of acute pancreatitis.
  • Contact a doctor immediately if you feel tired, have pale skin, bruises, uncontrolled bleeding, fever, sore throat, or feel generally unwell, as these could be signs of blood disorders.
  • Stop taking this medicine and contact your doctor if you experience tendon pain or inflammation (e.g., in your ankle, wrist, elbow, shoulder, or knee) and rest the affected area to avoid rupture.
  • Stop taking this medicine and tell your doctor immediately if you develop nerve damage symptoms (neuropathy) like pain, burning, tingling, numbness, or muscle weakness, especially in your feet, legs, hands, or arms.
  • If you experience any prolonged, disabling, or potentially permanent side effects, contact your doctor immediately before continuing treatment.
  • Avoid direct sunlight during treatment and for 2 days after, as your skin will be much more sensitive and may burn or blister easily.
  • Do not take iron tablets, zinc supplements, antacids, didanosine, or sucralfate at the same time as Levofloxacin Krka. Take them at least 2 hours before or after Levofloxacin Krka.
  • Consult an eye specialist immediately if your vision decreases or you experience other eye disturbances while taking Levofloxacin Krka.