Paliperidone STADA
Paliperidone Stada is a medicine used for long-term treatment of schizophrenia in adults, helping to manage symptoms and prevent them from returning.
Form
Injektioneste, depotsuspensio, esitäytetty ruisku
Strength
75 mg
Active Ingredient
Paliperidone palmitate
Manufacturer
STADA Arzneimittel AG
How to Use
Dosage
The first dose is 150 mg, and the second is 100 mg, given about one week apart. After that, you will receive a monthly injection of 25 mg to 150 mg.
Method
The first two injections are given into the upper arm. Subsequent monthly injections can be given into either the upper arm or the buttock.
Important
The maximum single dose given monthly is 150 mg.
Possible Side Effects
COMMON
- •Difficulty falling asleep or interrupted sleep.
- •Flu-like symptoms, urinary tract infection, general feeling of illness.
- •Swollen breasts, difficulty with erection or other sexual problems (in men); breast discomfort, milk discharge, missed periods (in women) due to high prolactin levels.
- •High blood sugar, weight gain, weight loss, decreased appetite.
- •Irritability, depression, anxiety.
- •Slow or stiff movements, shaking, drooling, or a mask-like face (Parkinsonism-like symptoms).
- •Feeling restless, drowsy, or less alert.
- •Slow, lasting muscle spasms, often in the face, eyes, tongue, or jaw (dystonia).
- •Dizziness.
- •Uncontrolled, repetitive, twisting, or twitching muscle movements (dyskinesia).
- •Headache.
- •Fast heart rate.
- •High blood pressure.
- •Cough, stuffy nose.
- •Stomach pain, vomiting, nausea, constipation, diarrhea, indigestion, toothache.
- •Increased liver enzyme levels in blood.
- •Bone or muscle pain, back pain, joint pain.
- •Missed periods.
- •Fever, weakness, or tiredness.
- •Itching, pain, or swelling at the injection site.
RARE
- •Pneumonia, bronchitis, respiratory infection, sinus infection, bladder infection, ear infection, nail fungus, tonsillitis, skin infection.
- •Low white blood cell count, anemia, increased eosinophils (a type of white blood cell), decreased platelets (blood cells that stop bleeding), dangerously low levels of certain white blood cells.
- •Allergic reaction, severe allergic reaction with fever, swelling of mouth, face, lips or tongue, shortness of breath, itching, rash, and sometimes drop in blood pressure.
- •New or worsening diabetes, high insulin levels, life-threatening complications of uncontrolled diabetes, low blood sugar, sugar in urine.
- •Increased appetite, loss of appetite leading to malnutrition and weight loss.
- •High triglyceride and cholesterol levels in blood.
- •Sleep disorders, elevated mood (mania), reduced sexual desire, nervousness, nightmares, confusion, sleepwalking, lack of emotions, inability to orgasm.
- •Jerky, uncontrolled movements of the face, tongue, or other body parts (tardive dyskinesia), head shaking.
- •Fainting, strong urge to move a body part, dizziness when standing, trouble concentrating, speech problems, loss or change of taste, reduced sensation in skin, tingling or numbness, abnormal coordination.
- •Blurred vision, eye infection, dry eyes, glaucoma (increased eye pressure), eye movement disorders, eye rolling, light sensitivity, increased tears, red eyes.
- •Spinning sensation (vertigo), ringing in ears, ear pain.
- •Heart rhythm problems (including atrial fibrillation), abnormal EKG, fast heart rate when standing, slow heart rate, fluttering or pounding in chest.
- •Low blood pressure, especially when standing up.
- •Shortness of breath, sore throat, nosebleed, sleep apnea, lung or airway congestion, wheezing, gasping.
- •Abdominal pain, stomach or intestinal infection, difficulty swallowing, dry mouth, excessive gas, pancreatitis, swollen tongue, inability to control bowel movements, very hard stool, intestinal blockage, chapped lips.
- •Increased CPK levels in blood.
- •Skin inflammation from mites, scaly itchy scalp or skin, drug rash, thickened skin, dandruff, hives, itching, rash, hair loss, eczema, dry or red skin, acne, pus under skin, skin hardening, skin discoloration, severe or life-threatening rash with blisters and peeling skin (Stevens-Johnson syndrome or toxic epidermal necrolysis).
- •Muscle cramps, stiff joints, muscle weakness, breakdown of muscle fibers and muscle pain (rhabdomyolysis), joint swelling.
- •Urinary incontinence, frequent or painful urination, inability to urinate.
- •Erectile dysfunction, ejaculation problems, missed periods or other menstrual problems (women), breast development in men, sexual dysfunction, breast pain, milk discharge, breast discomfort, enlarged or swollen breasts, vaginal discharge, prolonged erection (priapism) that may require surgery.
- •Swelling of face, mouth, eyes, lips, body, arms, or legs.
- •Increased body temperature, very low body temperature, chills, thirst.
- •Changes in how you walk, falls, abnormal posture.
- •Chest pain, chest discomfort, general feeling of being unwell.
- •Blood clots in the lungs (causing chest pain and difficulty breathing), blood clots in veins (especially legs, causing swelling, pain, and redness).
- •Neuroleptic malignant syndrome (confusion, reduced consciousness, high fever, severe muscle stiffness), cerebrovascular disorders (including stroke), unresponsiveness to stimuli, loss of consciousness, seizures, balance disorder.
- •Inappropriate secretion of hormone that regulates urine volume, excessive water drinking.
- •Catatonia (immobile and unresponsive while awake).
- •Flushing (feeling of warmth and redness in skin).
- •Drug withdrawal symptoms.
- •Damage to skin cells at the injection site, injection site ulcer.
Important Warnings
- This medicine is not for elderly patients with dementia, as it may increase their risk of stroke or death.
- Tell your doctor if you have Parkinson's disease.
- Tell your doctor if you have a history of fever with muscle stiffness (Neuroleptic Malignant Syndrome).
- Tell your doctor if you have had unusual face or tongue movements (Tardive Dyskinesia).
- Tell your doctor if you have had a low white blood cell count.
Show 18 more warnings
- Tell your doctor if you have diabetes or are at risk of getting diabetes.
- Tell your doctor if you have had breast cancer or a pituitary gland tumor.
- Tell your doctor if you have heart problems or low blood pressure.
- Tell your doctor if you have low blood pressure when standing up quickly.
- Tell your doctor if you have epilepsy.
- Tell your doctor if you have kidney or liver problems.
- Tell your doctor if you have had a prolonged and painful erection.
- Tell your doctor if you have trouble regulating your body temperature or if you overheat easily.
- Tell your doctor if you have high prolactin levels in your blood or a prolactin-dependent tumor.
- Tell your doctor if you or your family have a history of blood clots.
- Seek immediate medical help if you get a rash, throat swelling, itching, or difficulty breathing, as these can be signs of a severe allergic reaction.
- This medicine can cause weight gain; your weight will be checked regularly.
- This medicine can cause or worsen diabetes; your blood sugar will be monitored.
- This medicine may hide signs of poisoning or other illnesses by reducing your urge to vomit.
- If you are having eye surgery, tell your eye doctor that you are taking this medicine.
- Do not use this medicine if you are pregnant unless your doctor says it is safe.
- Do not breastfeed while using this medicine.
- This medicine can make you dizzy, tired, or blur your vision, so be careful when driving or using machines.