Neurotol slow
Neurotol contains carbamazepine and is used to prevent epileptic seizures and treat nerve pain, alcohol withdrawal symptoms, restlessness in children, and the manic phase of bipolar disorder.
Form
tabletti
Strength
200 mg
Active Ingredient
Carbamazepine
Manufacturer
Orion Corporation
How to Use
Dosage
Your doctor will prescribe a personal dose based on your illness, its severity, and your age; treatment usually starts with a small dose and is gradually increased as needed.
Method
Take tablets whole or divided with liquid (e.g., half a glass of water) at mealtimes, after meals, or on an empty stomach; do not chew or crush.
Important
Do not exceed the dose prescribed by your doctor.
Possible Side Effects
COMMON
- •Low white blood cell count (leukopenia)
- •Dizziness, problems with muscle coordination (ataxia), drowsiness, fatigue
- •Nausea, vomiting
- •Elevated liver enzyme levels (gamma-GT value)
- •Allergic skin inflammation, hives
- •Low platelet count (thrombocytopenia), increased count of certain white blood cells (eosinophilia)
- •Swelling, fluid retention, weight gain, low blood sodium, reduced blood concentration (which can lead to water intoxication with drowsiness, vomiting, headache, confusion, and neurological problems)
- •Headache
- •Double vision, decreased visual acuity, blurred vision
- •Dry mouth
- •Elevated liver enzyme levels (AFOS values)
RARE
- •Abnormal involuntary movements (e.g., tremor, muscle twitching), nystagmus (involuntary eye movements)
- •Diarrhea, constipation
- •Elevated liver enzyme levels (transaminase values)
- •Exfoliative dermatitis, red skin
- •Increased white blood cell count (leukocytosis), swollen lymph nodes (lymphadenopathy)
- •Delayed multi-organ hypersensitivity reactions with symptoms like fever, rash, vasculitis, swollen lymph nodes, pseudo-lymphoma, joint pain, low white blood cell count, increased granulocytes, enlarged liver or spleen, abnormal liver values, and bile duct destruction (can also affect lungs, kidneys, pancreas, heart muscle, or large intestine)
- •Folic acid deficiency, decreased appetite
- •Visual or auditory hallucinations, depression, restlessness, aggressiveness, agitation, confusion
- •Epileptic seizures, absence seizures, memory and intellectual impairments, psychomotor disturbances, involuntary mouth and facial movements (dyskinesia), eye movement disorders, speech disorders (e.g., dysarthria, slurred speech), movement disorders (choreoathetosis), numbness, tingling, burning, or weakness in hands and feet (peripheral neuropathy), abnormal sensations (paresthesia), partial paralysis (paresis)
- •Heart rhythm disorders, heart conduction disorders
- •Low or high blood pressure
- •Upper abdominal pain
- •Jaundice, liver inflammation (hepatitis), liver tissue necrosis, liver damage
- •Autoimmune disease SLE, itching
- •Muscle weakness
- •Itching
- •Agranulocytosis, complete lack or low count of all blood cells, complete lack of red blood cells, anemia (low blood cell count), megaloblastic anemia (due to B12 vitamin or folic acid deficiency), increased young red blood cells
- •Life-threatening hypersensitivity reactions (anafylaxis), episodic local skin swelling, low blood gammaglobulin
- •Breast growth in men, milk discharge in women
- •Thyroid disorders
- •Metabolic disorders characterized by high porphyrin content in blood and urine
- •Activation of psychosis
- •Neuroleptic malignant syndrome (symptoms include reduced movement, muscle stiffness, difficulty swallowing, sweating, reduced consciousness, fever, blood pressure fluctuations)
- •Non-bacterial meningitis
- •Clouding of the eye lens, conjunctivitis
- •Hearing disorders, tinnitus, sensitive or poor hearing, changes in pitch perception
- •Taste disorders
- •Slow heart rate (bradycardia), arrhythmias, AV block, heart failure, worsening of coronary artery disease
- •Fainting due to circulatory disorder, venous inflammation (thrombophlebitis), venous thrombosis (thromboembolism)
- •Lung hypersensitivity reactions (typical symptoms include fever, shortness of breath, lung inflammation or pneumonia)
- •Tongue and mouth inflammation, pancreatitis
- •Liver inflammation, liver failure
- •Severe skin reactions like Stevens-Johnson syndrome and toxic epidermal necrolysis; skin photosensitivity reactions; erythema nodosum; skin pigment changes; purpura; acne; excessive sweating; hair loss; hirsutism; joint pain, muscle pain or muscle cramps
- •Bone metabolic disorders that can lead to bone loss (osteoporosis)
- •Kidney failure, nephritis, impaired kidney function (symptoms e.g., blood in urine, decreased urine output, elevated blood urea), changes in urination frequency, urinary retention
- •Sexual disorders, erectile dysfunction, decreased sperm count and/or motility
- •Increased intraocular pressure, elevated blood cholesterol and triglyceride levels, thyroid dysfunction, elevated blood prolactin levels
- •Hypogammaglobulinemia (low blood gammaglobulin)
- •Reactivation of herpes virus infection (can be serious if the immune system is suppressed)
- •Bone marrow failure
- •Falls
- •Memory problems
- •Colon inflammation
- •Drug hypersensitivity reaction with red rash, skin peeling, and fever
- •Drug hypersensitivity reaction with red or blistered skin that spreads from face to body
- •Lichen planus-like skin inflammation
- •Nail detachment
- •Decreased bone density and bone fractures
- •High blood ammonia levels (hyperammonemia), with symptoms like irritability, confusion, vomiting, loss of appetite, and drowsiness.
Important Warnings
- Do not take Neurotol if you are allergic to carbamazepine, tricyclic antidepressants, or any other ingredient in this medicine.
- Do not take Neurotol if you have severe heart disease.
- Do not take Neurotol if you have a heart conduction disorder (e.g., AV block).
- Do not take Neurotol if you have or have had bone marrow problems or porphyria (a metabolic disease).
- Do not use Neurotol together with MAO inhibitors (e.g., selegiline or moclobemide).
Show 19 more warnings
- Talk to your doctor if you have or have had glaucoma, difficulty urinating, or pain when urinating.
- Talk to your doctor if you have or have had heart, liver, or kidney disease.
- Talk to your doctor if you have been sensitive to oxcarbazepine or other medicines before (e.g., rash or other allergic symptoms), as you might also react to Neurotol.
- Talk to your doctor if you have a blood disorder.
- Talk to your doctor if you have had psychosis, as Neurotol can activate hidden psychosis and cause confusion or agitation in older patients.
- Talk to your doctor if you are of Chinese or Thai origin, as a blood test may be needed to check your risk of severe skin reactions.
- Talk to your doctor if you are pregnant or planning to get pregnant, as Neurotol can harm the baby; effective contraception is needed during treatment and for two weeks after.
- If you develop a rash or other skin problems, stop using carbamazepine immediately and contact your doctor.
- If you have developed Stevens-Johnson syndrome or toxic epidermal necrolysis while using Neurotol, you must never use Neurotol again.
- If you experience fever, sore throat, rash, bruising, easy bleeding, or bleeding from mouth membranes, contact your doctor or the nearest emergency room immediately.
- Seek immediate medical attention for allergic reactions like swelling of the lips, eyelids, face or mouth, sudden shortness of breath, fever with swollen lymph nodes, rash, or skin blisters.
- Seek immediate medical attention if you experience increased epileptic seizures.
- Seek immediate medical attention if you have suicidal thoughts or thoughts of harming yourself.
- Seek immediate medical attention for symptoms resembling liver inflammation, such as yellowing of the skin and whites of the eyes.
- Seek immediate medical attention if you experience irregular bleeding or spotting from the vagina, as this medicine may reduce the effectiveness of hormonal contraceptives.
- Seek immediate medical attention for kidney problems, especially with low blood sodium, or if you use certain diuretics that lower blood sodium.
- Seek immediate medical attention for dizziness, drowsiness, low blood pressure, or confusion caused by treatment, as these can lead to falls.
- Long-term Neurotol use can cause vitamin D deficiency and weaken bones, so ensure adequate vitamin D intake during treatment.
- Do not stop Neurotol treatment without talking to your doctor, as suddenly stopping can increase seizures.
Use in Elderly Patients
Category D
Avoid use in older adults. Hyponatraemia is a common adverse effect. Numerous potential adverse effects, such as hematological changes and risk of hepatic injury. May increase the need for a vitamin D supplement. Consider the numerous potential and significant interactions before starting and discontinuing the use. Avoid grapefruit. (updated 10.11.2025)