Naproxen Krka
Naproxen Krka is an NSAID painkiller used to treat inflammation, pain, migraines, menstrual pain, heavy periods, rheumatic diseases, osteoarthritis, and gout.
Form
tabletti, kalvopäällysteinen
Strength
550 mg
Active Ingredient
Naproxen sodium
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
The usual daily dose is 1 or 2 tablets (550 mg or 1100 mg naproxen sodium), divided into morning and evening doses.
Method
Take tablets by mouth, with or without food. Taking it with food may slow down its effect.
Important
Do not exceed 2.5 tablets (1375 mg naproxen sodium) per day.
Possible Side Effects
COMMON
- •Heartburn, pain in the upper stomach, nausea, vomiting, diarrhea, constipation.
- •Bleeding or ulcers in the digestive tract.
- •Bruising, itching, red spots on the skin.
- •Difficulty sleeping (insomnia).
- •Dizziness, headache, lightheadedness.
- •Vision disturbances.
- •Sudden rashes, allergic rashes, sweating.
- •Hearing impairment, hearing problems, ringing in ears (tinnitus), spinning sensation (vertigo).
RARE
- •Holes in the digestive tract, vomiting blood, bloody stools, mouth inflammation, worsening of ulcerative colitis and Crohn's disease.
- •Increased potassium in blood (hyperkalemia).
- •Depression, abnormal dreams.
- •Optic nerve inflammation behind the eyeball, seizures, problems with thinking and concentration.
- •Palpitations (fast or strong heartbeat).
- •Fluid in the lungs (pulmonary edema).
- •Asthma, a type of pneumonia with increased eosinophils.
- •Abnormal liver function test results.
- •Hair loss.
- •Kidney problems like kidney inflammation, kidney disease where too much protein is lost, or kidney failure.
- •Female infertility, menstrual disorders.
- •Thirst, feeling unwell.
- •Increased creatinine levels in blood.
- •Cloudy cornea, inflamed or swollen optic nerve.
- •Skin reactions to light, with or without flaky or blistering skin symptoms.
- •Muscle pain, muscle weakness.
- •Inflammation of salivary glands, pancreas.
- •Non-bacterial meningitis, fever and chills.
- •Changes in blood cell counts (agranulocytosis, aplastic anemia, hemolytic anemia, eosinophilia, leukocytopenia, thrombocytopenia).
- •Severe allergic reactions with swelling (angioedema) and shortness of breath.
- •Drowsiness.
- •Heart failure.
- •Blood clots (e.g., heart attack or stroke), high blood pressure, inflammation of blood vessels (vasculitis).
- •Fatal liver inflammation, jaundice (yellowing of skin/eyes).
- •Severe blistering skin reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, erythema nodosum, scaling eczema, blistering reactions, lupus (SLE), hives.
- •Kidney tissue damage (papillary necrosis), blood in urine, kidney disease.
- •Widespread rash, fever, elevated liver enzymes, abnormal blood counts (eosinophilia), enlarged lymph nodes and effects on other organs (DRESS syndrome).
- •Fixed drug eruption (a specific allergic skin reaction that reappears in the same spot, appearing as red, swollen, round or oval patches or blisters).
Important Warnings
- Do not take if you are allergic to naproxen sodium or any other ingredients in this medicine, or if you have had an allergic reaction (like asthma, runny nose, or rash) to aspirin or similar painkillers before.
- Do not take if you have or have had stomach or duodenal ulcers, or bleeding in your digestive system.
- Do not take if you have severe heart failure.
- Do not use during the last three months of pregnancy, as it may harm your unborn baby or cause problems during delivery.
- This medicine may slightly increase the risk of heart attack or stroke, especially with high doses or long-term use. Do not exceed the recommended dose or treatment time.
Show 6 more warnings
- Talk to your doctor if you have heart problems, a history of stroke, high blood pressure, diabetes, high cholesterol, or smoke. Also, tell your doctor if you have digestive tract ulcers, asthma, increased bleeding tendency, or kidney/liver disease.
- Elderly patients are more prone to side effects; long-term use of NSAIDs is not recommended for them.
- Stop taking this medicine immediately if you develop a rash, changes in mucous membranes, or other allergic reactions.
- Do not give this medicine to children under 5 years old.
- This medicine is not recommended during breastfeeding because naproxen passes into breast milk.
- This medicine may affect your ability to drive or operate machinery. Be careful until you know how it affects you.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. For short-term use only. Consider adverse renal effect in chronic kidney disease. Do not use in severe renal impairment. Increases swelling, worsens renal and heart failure and causes cardiovascular events. Increases risk of bleeding, especially in the gastrointestinal tract. Consider potential interactions especially with preparations that increase risk of bleeding. (updated 16.9.2024)