Moxifloxacin Krka
Moxifloxacin Krka is an antibiotic that kills bacteria causing infections.
Form
infuusioneste, liuos
Strength
400 mg / 250 ml
Active Ingredient
Moxifloxacin hydrochloride
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
The recommended dose for adults is one bottle once a day.
Method
Moxifloxacin Krka is given as an infusion into a vein by a doctor or nurse over 60 minutes.
Important
Do not exceed one bottle (400 mg) per day.
Possible Side Effects
COMMON
- •Nausea
- •Diarrhea
- •Dizziness
- •Stomach and abdominal pain
- •Vomiting
- •Headache
- •Increase in certain liver enzymes in the blood
- •Infections caused by resistant bacteria or fungi (e.g., oral or vaginal yeast infection)
- •Pain or inflammation at the injection site
- •Changes in heart rhythm (ECG) in patients with low blood potassium
- •Rash
- •Stomach problems (indigestion or heartburn)
- •Taste disturbances (very rarely loss of taste)
- •Sleep disturbances (mainly insomnia)
- •Increase in certain liver enzymes in the blood
- •Decrease in certain white blood cells
- •Constipation
- •Itching
- •Feeling of dizziness (spinning sensation or risk of falling)
- •Drowsiness
- •Flatulence
- •Heart rhythm changes (EKG)
- •Impaired liver function (including increase in certain liver enzymes in the blood)
- •Decreased appetite and reduced food intake
- •Decrease in white blood cell count
- •Pain and ache (e.g., in back, chest, pelvis, and limbs)
- •Increase in blood cells important for blood clotting
- •Sweating
- •Increase in certain white blood cells (eosinophils)
- •Anxiety
- •Malaise (mainly weakness or fatigue)
- •Tremor
- •Joint pain
- •Palpitations
- •Irregular or fast heart rate
- •Difficulty breathing (including asthmatic symptoms)
- •Increase in certain digestive enzymes in the blood
- •Restlessness or agitation
- •Tingling and/or numbness
- •Hives
- •Widening of blood vessels
- •Confusion and disorientation
- •Decrease in certain blood cells affecting blood clotting
- •Visual disturbances (including double vision and blurred vision)
- •Impaired blood clotting
- •Increase in blood lipids (fats)
- •Decrease in red blood cells
- •Muscle pain
- •Allergic reactions
- •Increase in bilirubin in the blood
- •Inflammation in a vein
- •Stomach inflammation
- •Dehydration
- •Severe heart rhythm abnormality
- •Dry skin
- •Chest pain (angina pectoris)
RARE
- •Muscle twitching
- •Muscle cramps
- •Hallucinations
- •High blood pressure
- •Swelling (hands, feet, ankles, lips, mouth, throat)
- •Low blood pressure
- •Kidney failure (including increased kidney lab values)
- •Liver inflammation
- •Mouth inflammation
- •Ringing/noise in the ears
- •Jaundice (yellowing of skin or whites of eyes)
- •Reduced skin sensation
- •Abnormal dreams
- •Impaired concentration
- •Difficulty swallowing
- •Change in sense of smell (including loss of smell)
- •Balance or coordination disorder (due to dizziness)
- •Partial or complete memory loss
- •Hearing loss including deafness (usually reversible)
- •Increase in uric acid in blood
- •Mood changes
- •Speech difficulties
- •Fainting
- •Muscle weakness
- •Joint inflammation (arthritis)
- •Abnormal heart rhythm
- •Increased skin sensitivity
- •Feeling of being outside oneself (alienation)
- •Increased blood clotting
- •Muscle stiffness
- •Significant decrease in white blood cells (agranulocytosis)
- •Decrease in red and white blood cells and platelets (pancytopenia)
Important Warnings
- Do not use if you have had severe side effects from similar antibiotics (quinolones) before. Tell your doctor right away.
- This medicine can affect your heart rhythm. Tell your doctor if you have heart problems or low potassium.
- Tell your doctor if you have a bulging blood vessel (aneurysm) or a leaking heart valve.
- If you have epilepsy or a history of seizures, tell your doctor.
- Talk to your doctor if you have ever had mental health problems.
Show 17 more warnings
- If you have myasthenia gravis (a muscle weakness condition), this medicine may make it worse.
- This medicine is only given into a vein, never into an artery.
- If you have diabetes, monitor your blood sugar carefully as it may change.
- If you've had severe skin reactions like rash, peeling skin, or blisters from moxifloxacin before, tell your doctor.
- If you feel your heart racing or beating irregularly, contact your doctor immediately.
- Seek immediate medical help if you experience a severe allergic reaction (chest tightness, dizziness, nausea, fainting).
- This medicine can cause severe liver problems. Seek medical help if you feel suddenly unwell or notice yellow skin/eyes, dark urine, itching, or bleeding easily.
- This medicine can cause seizures. If this happens, stop treatment and tell your doctor.
- This medicine can cause long-lasting problems like tendon or muscle pain, joint pain, trouble walking, strange feelings like tingling, or problems with sight, taste, smell, hearing, memory, or mood. If you get any of these, stop taking the medicine and tell your doctor right away.
- If you get severe or bloody diarrhea, stop taking the medicine and contact your doctor immediately. Do not take anti-diarrhea medicine.
- Tendon pain or swelling, especially in ankles, wrists, elbows, shoulders, or knees, can happen. If you feel this, stop the medicine and contact your doctor.
- If you get sudden, severe pain in your stomach, chest, or back, go to the emergency room right away.
- Contact your doctor immediately if you have sudden shortness of breath, swelling in your ankles or belly, or new fast/irregular heartbeats.
- If your vision gets worse or you have other eye problems, see an eye doctor right away.
- If you have diabetes, this medicine can affect your blood sugar levels. Monitor them closely.
- Your skin may become more sensitive to sun or UV light. Avoid prolonged sun exposure and tanning beds.
- Not for use in children and adolescents under 18 years.
Use in Elderly Patients
Category D
Avoid use in older adults. Risk of QT prolongation. Reduce the dose and/or increase the dosing interval in moderately severe renal impairment. Calcium, iron, zinc, magnesium and aluminium reduce absorption. Increases the risk of tendinitis and aortic injury and valvular heart disease. Consider central nervous system adverse effects, especially lowered seizure threshold and confusion. (updated 4.12.2023)