Enanton Depot Dual
Enanton Depot Dual is an injectable medicine containing leuprorelin acetate, a man-made hormone that reduces testosterone and estrogen levels in the body.
Form
injektiokuiva-aine ja liuotin suspensiota varten, esitäytetty ruisku
Strength
3.75 mg
Active Ingredient
Leuprorelin acetate
Manufacturer
Orion Corporation
How to Use
Dosage
Your doctor will decide your dose. For adults, it's typically 3.75 mg every 4 weeks or 11.25 mg every 3 months. For children over 20 kg, it's 3.75 mg (1 ml) once a month or 11.25 mg (1 ml) once every 3 months.
Method
This medicine is given as an injection under the skin by a doctor or nurse.
Important
This medicine is not taken daily. The maximum single dose is 3.75 mg or 11.25 mg, given periodically as prescribed by your doctor.
Possible Side Effects
COMMON
- •Mood changes
- •Depression
- •Sleeplessness
- •Hot flashes
- •Sweating
- •Muscle weakness
- •Decreased sexual desire and ability
- •Injection site reactions (pain, hardening, redness)
- •Feeling hot
- •Headache
- •Dizziness
- •Tingling or numbness of skin
- •Stomach pain or cramps
- •Nausea or vomiting
- •Acne
- •Vaginal bleeding
- •Breakthrough bleeding or spotting
- •Vaginal discharge
- •Breast tenderness
- •Weight changes
- •Joint pain
- •Bone pain
- •Stiffness (e.g., shoulders, back, limbs)
RARE
- •Increased levels of LDH enzyme
- •Liver problems (jaundice)
- •Smaller testicles
- •Anemia
- •Decreased platelets
- •Loss of appetite
- •Increased blood triglycerides, cholesterol, sugar, potassium, or uric acid
- •Deafness
- •Ringing in ears (tinnitus)
- •Changes in ECG (heart's electrical activity)
- •Enlarged heart
- •Facial flushing
- •Increased bilirubin and liver enzyme levels
- •Skin inflammation
- •Increased hair growth (hirsutism)
- •Rash
- •Itching
- •Frequent urination
- •Blood in urine
- •Increased urea in blood
- •Breast enlargement
- •Uncomfortable feeling in pelvic area
- •Difficulty walking
- •Swelling
- •Chest pressure
- •General discomfort
- •Fever
- •Hypersensitivity (severe allergic reaction)
- •Hives (nettle rash)
- •Wheezing or breathing difficulties
- •Chills
- •Anaphylactic reaction (severe, whole-body allergic reaction)
- •Blood clot
- •Lung blood clot (pulmonary embolism)
- •Diarrhea
- •Injection site abscess (pus-filled lump)
- •Pituitary stroke (bleeding and tissue death in the pituitary gland)
- •Metabolic syndrome (high blood pressure, high lipids)
- •Insulin resistance or impaired glucose tolerance
- •Fatty liver
- •Epileptic seizure
- •Vision impairment or double vision
- •Palpitations (fast or irregular heartbeat)
- •Changes in ECG (prolonged QT interval)
- •Lung inflammation or lung disease
- •Bone loss (including spinal fractures) or decreased bone mineral density
- •Increased pressure inside the skull (idiopathic intracranial hypertension), symptoms include headache, double vision, other visual disturbances, or ringing in ears
- •Changes in blood count (increased red blood cells, decreased white blood cells and platelets, prolonged blood clotting time)
- •Numbness in limbs
- •Carpal tunnel syndrome
- •High blood pressure
- •Abdominal pain
- •Feeling of bloating in the stomach
- •Constipation
- •Mouth inflammation
- •Numbness of lips
- •Dry skin
- •Hair loss
- •Excessive hair growth
- •Nail changes
- •Lower back pain
- •Leg pain
- •Painful urination
- •Painful intercourse
- •Increased vaginal discharge
- •Ovarian hyperstimulation syndrome
- •Breast swelling or reduction in breast tissue
- •Uncomfortable feeling in the chest area
- •Thirst
Important Warnings
- Do not use if you are allergic to leuprorelin acetate, any other ingredients in this medicine, or similar substances.
- Do not use if you have unexplained vaginal bleeding.
- Do not use if you are pregnant, suspect you are pregnant, or are breastfeeding. Women who can get pregnant must use effective contraception during treatment.
- Tell your doctor if you have a urinary tract obstruction.
- Tell your doctor if you have a spinal cord injury.
Show 13 more warnings
- Tell your doctor if you have diabetes.
- Tell your doctor if you have an increased risk of metabolic, heart, or blood vessel problems, including heart rhythm disorders, or if you are being treated for these conditions.
- Tell your doctor if you have osteoporosis and a higher risk of bone fractures.
- Tell your doctor if you have epilepsy or have had epileptic seizures.
- Tell your doctor if you have a fatty liver.
- Depression, which can be severe, has been reported with this medicine. Tell your doctor if you feel depressed.
- If you (or your child) experience severe or repeated headaches, vision problems, or ringing in the ears, contact a doctor immediately.
- Severe skin rashes, including Stevens-Johnson syndrome or toxic epidermal necrolysis, have been reported. Stop using the medicine and seek medical help immediately if you notice any related symptoms.
- If the treated child has a brain tumor, the benefits and risks of treatment must be carefully considered.
- Tell your doctor if you notice an abscess at the injection site.
- This medicine may cause a decrease in bone mineral density (bones may become weaker).
- Enanton Depot Dual may affect your ability to drive or use machines, as it can cause fatigue, vision problems, and dizziness.
- In rare cases, this medicine may contain gelatin or polysorbate, which can cause severe allergic reactions. Tell your doctor about any known allergies.