Dimethyl fumarate Sandoz
Dimethyl fumarate Sandoz treats a type of multiple sclerosis (MS) in patients 13 years and older.
Form
enterokapseli, kova
Strength
240 mg
Active Ingredient
Dimethyl fumarate
Manufacturer
Sandoz A/S
How to Use
Dosage
Start with 120 mg twice a day for 7 days. After that, take 240 mg twice a day.
Method
Swallow capsules whole with water, do not crush or chew. Take with food to reduce side effects.
Important
The maximum daily dose is 480 mg.
Possible Side Effects
COMMON
- •Flushing, feeling warm, burning, or itching in the body
- •Diarrhea
- •Nausea
- •Stomach pain or cramps
- •Inflammation of the stomach and intestines (gastroenteritis)
- •Vomiting
- •Indigestion (dyspepsia)
- •Stomach lining inflammation (gastritis)
- •General stomach discomfort
- •Burning sensation in the body
- •Hot flashes, feeling hot
- •Skin itching
- •Rash
- •Red or pinkish patches on the skin (erythema)
- •Hair loss (alopecia)
- •Low white blood cell count
- •Protein in urine
- •Increased liver enzymes in blood
- •Ketones in urine
- •Headache (more often reported in children and adolescents)
- •Sore throat (more often reported in children and adolescents)
- •Cough (more often reported in children and adolescents)
- •Painful menstruation (more often reported in children and adolescents)
RARE
- •Severe allergic reaction (e.g., swelling of face/lips/tongue, wheezing, trouble breathing, dizziness, fainting)
- •Low platelet count
- •Liver inflammation with increased liver enzymes (combined with bilirubin)
- •Shingles (Herpes zoster), with symptoms like blisters, burning, itching, or pain in the skin, fever, weakness, numbness, or red spots with severe pain
- •Runny nose
Important Warnings
- Do not take if you are allergic to dimethyl fumarate or any other ingredients in this medicine.
- Do not take if you are suspected of having or have a rare brain infection called PML.
- Tell your doctor if you have severe kidney, liver, stomach, or bowel disease, or a severe infection like pneumonia.
- Contact your doctor immediately if you suspect shingles (Herpes zoster) or if your MS symptoms worsen or you notice new symptoms, as these could be signs of a serious brain infection (PML).
- Watch for symptoms of a rare kidney disease (Fanconi syndrome), such as increased urination, thirst, muscle weakness, or bone pain, and tell your doctor if they occur.
Show 4 more warnings
- This medicine should not be given to children under 10 years old.
- Avoid strong alcoholic drinks for one hour before and after taking this medicine, as it can cause stomach inflammation (gastritis).
- Avoid live vaccines while taking this medicine, as it may increase your risk of infection.
- Your doctor will check your white blood cell count, kidney, and liver function regularly.