Celecoxib Viatris
Celecoxib Viatris is a pain reliever that reduces swelling and pain in adults with conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
Form
kapseli, kova
Strength
100 mg
Active Ingredient
Celecoxib
Manufacturer
Upjohn EESV
How to Use
Dosage
The usual dose is 200 mg daily for osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. This can be taken as one 200 mg capsule once daily, or one 100 mg capsule twice daily. Your doctor may increase the dose if needed.
Method
Take Celecoxib Viatris capsules by mouth with or without food, preferably at the same time each day. If you have trouble swallowing, you can open the capsule and mix its contents with a spoonful of semi-solid food (like applesauce or yogurt) and swallow immediately with about 240 ml of water. Do not chew or crush the granules.
Important
Do not take more than 400 mg per day.
Possible Side Effects
COMMON
- •High blood pressure or worsening of existing high blood pressure.
- •Heart attack.
- •Fluid retention, causing swelling in ankles, legs, and/or hands.
- •Urinary tract infection.
- •Shortness of breath, sinusitis, blocked nose, runny nose, sore throat, cough, cold or flu-like symptoms.
- •Dizziness, trouble sleeping.
- •Vomiting, stomach pain, diarrhea, indigestion, gas.
- •Rash, itching.
- •Muscle stiffness.
- •Difficulty swallowing.
- •Headache.
- •Nausea (feeling sick).
- •Joint pain.
- •Worsening of existing allergies.
- •Accident.
RARE
- •Stroke.
- •Heart failure, rapid heartbeat or palpitations (feeling your heart beat fast).
- •Abnormal liver or kidney blood test results.
- •Anemia (low red blood cells, causing tiredness or shortness of breath).
- •Anxiety, depression, tiredness, drowsiness, tingling or prickling feeling in the skin.
- •High potassium levels in blood (may cause nausea, tiredness, muscle weakness, or fast heartbeat).
- •Blurred or reduced vision, ringing in the ears, mouth sores or ulcers, difficulty hearing.
- •Constipation, burping, stomach inflammation (indigestion, stomach pain, vomiting), worsening of stomach or bowel inflammation.
- •Leg cramps.
- •Raised itchy rash (hives).
- •Eye inflammation.
- •Breathing difficulties.
- •Skin discoloration (bruises).
- •Chest pain (general pain not related to the heart).
- •Swelling of the face.
- •Stomach, esophagus, or bowel ulcers (bleeding) or perforation (may cause stomach pain, fever, nausea, vomiting, bowel blockage), dark or black stools, inflammation of the pancreas (pancreatitis, may cause stomach pain), inflammation of the esophagus.
- •Low sodium levels in the blood (hyponatremia).
- •Decreased white blood cells (which fight infections) or platelets (increased risk of bleeding or bruising).
- •Difficulty coordinating muscle movements.
- •Confusion, changes in taste.
- •Increased sensitivity to light.
- •Hair loss.
- •Hallucinations.
- •Bleeding in the eye.
- •Acute reaction that may lead to lung inflammation.
- •Irregular heartbeat.
- •Redness and flushing.
- •Blood clots in the lung arteries (may cause sudden shortness of breath, sharp pain when breathing, or fainting).
- •Bleeding in the stomach or intestines (may cause blood in stools or vomit), small or large intestine inflammation.
- •Severe liver inflammation (hepatitis). Symptoms may include nausea, diarrhea, jaundice (yellow skin or eyes), dark urine, pale stools, bleeding tendency, itching, or chills.
- •Acute kidney failure.
- •Menstrual disorders.
- •Swelling of the face, lips, mouth, tongue, or throat, wheezing, or difficulty swallowing.
- •Very severe allergic reactions (including potentially fatal anaphylactic shock).
- •Severe skin diseases like Stevens-Johnson syndrome, peeling skin inflammation, toxic epidermal necrolysis (skin rash, blistering or peeling), and sudden widespread pus-filled rash (swollen red area with many small pus-filled bumps).
- •Delayed allergic reaction, possibly with symptoms like rash, facial swelling, fever, swollen lymph nodes, and abnormal test results (e.g., liver or blood cell tests).
- •Life-threatening bleeding in the brain.
- •Meningitis (inflammation of the membranes around the brain and spinal cord).
- •Liver failure, liver damage, and severe liver inflammation (fulminant hepatitis) (sometimes fatal or requiring liver transplant). Symptoms may include nausea, diarrhea, jaundice (yellow skin or eyes), dark urine, pale stools, bleeding tendency, itching, or chills.
- •Liver problems like cholestasis or cholestatic hepatitis, which may include symptoms such as discolored stools, nausea, and yellow skin or eyes.
- •Kidney inflammation and other kidney problems (e.g., nephrotic syndrome and minimal change disease) which may include fluid retention (swelling), foamy urine, tiredness, and loss of appetite.
- •Worsening of epilepsy (possibly increased frequency and/or severity of seizures).
- •Blocked artery or vein in the eye, leading to partial or complete vision loss.
- •Blood vessel inflammation (vasculitis), which may cause fever, aches, or purple-red spots on the skin.
- •Reduced red blood cells, white blood cells, and platelets (may cause tiredness, bruising, nosebleeds, and increased infection risk).
- •Muscle pain and weakness.
- •Reduced sense of smell.
- •Loss of taste.
- •Decreased fertility in women, usually reversible after stopping the medicine.
- •Other severe skin reactions such as fixed drug eruption (a specific allergic skin reaction that typically reappears in the same area each time the medicine is taken, appearing as red, swollen, round or oval patches with blisters or itching) and generalized bullous fixed drug eruption (may involve widespread skin reactions).
Important Warnings
- Do not take if you are allergic to celecoxib or any other ingredients in this medicine.
- Do not take if you have had an allergic reaction to medicines called sulfonamides (e.g., certain antibiotics).
- Do not take if you currently have stomach or bowel ulcers or bleeding.
- Do not take if you have asthma, nasal polyps, severe nasal congestion, or an allergic reaction (like an itchy rash, swelling of the face, lips, tongue or throat, or wheezing) after taking aspirin or other pain-relieving medicines (NSAIDs).
- Do not take if you are pregnant or planning to become pregnant.
Show 6 more warnings
- Do not take if you are breastfeeding.
- Do not take if you have severe liver disease.
- Do not take if you have severe kidney disease.
- Do not take if you have inflammatory bowel disease (like ulcerative colitis or Crohn's disease).
- Do not take if you have heart failure, known ischemic heart disease, or cerebrovascular disease (e.g., diagnosed heart attack, stroke, TIA, chest pain, or blockage in heart/brain blood vessels).
- Do not take if you have or have had blood circulation problems (peripheral arterial disease) or have had surgery on leg arteries.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. For short-term use only. Consider adverse renal effect in chronic kidney disease. Do not use in severe renal impairment. May increase swelling. Worsens renal and cardiac failure and causes cardiovascular events. Risk of gastrointestinal bleeding less than with traditional NSAIDs. Consider potential interactions especially with preparations that increase risk of bleeding. (updated 16.9.2024)