Balance 4.25 % Glukoosi, 1.25 Mmol/L Kalsium
Balance is a solution used for blood purification in patients with kidney failure through peritoneal dialysis, where the abdominal lining helps clean the blood.
Form
peritoneaalidialyysineste
Active Ingredient
Sodium chloride
Manufacturer
Fresenius Medical Care Deutschland GmbH
How to Use
Dosage
Typical dose is 2000–3000 ml of solution four times a day, depending on weight and kidney function, or as prescribed by your doctor.
Method
The solution is administered into the abdominal cavity (intraperitoneally). The solution bag has two chambers that must be mixed according to instructions before use.
Important
Up to 3000 ml per exchange, with up to 10 exchanges per day, or as directed by your doctor. The doctor may reduce the amount of solution if you feel abdominal tension.
Possible Side Effects
COMMON
- •Peritonitis, which may present as cloudy dialysate, abdominal pain, fever, general malaise, or rarely blood poisoning.
- •Inflammation at the catheter exit site or tunnel, with symptoms such as redness, swelling, pain, discharge, or hardening.
- •Hernia.
- •Problems related to dialysate inflow and outflow.
- •Abdominal distension or feeling of fullness.
- •Shoulder pain.
- •Potassium deficiency.
- •High blood sugar levels.
- •High blood fat levels.
- •Weight gain.
RARE
- •Diarrhea.
- •Constipation.
- •Calcium deficiency.
- •Decrease in body fluid levels, recognizable by rapid weight loss, low blood pressure, or fast heart rate.
- •Increase in body fluid levels, which may cause swelling in tissues and lungs, high blood pressure, or breathing difficulties.
- •Dizziness.
- •Blood poisoning.
- •Breathing difficulties.
- •Malaise (general feeling of being unwell).
- •Encapsulating peritoneal sclerosis, with possible symptoms of abdominal pain, abdominal distension, or vomiting.
- •Overactive parathyroid gland, which can lead to bone disorders.
Important Warnings
- Do not use balance 4.25% glucose, 1.25 mmol/l calcium if your blood potassium or calcium levels are very low, if your body fluid levels are too low, if you have low blood pressure, or if you have a metabolic disorder called lactic acidosis.
- Peritoneal dialysis should generally not be started if you have recent abdominal injury or surgery, severe burns, extensive inflammatory skin reactions, peritonitis, unhealed leaking wounds, hernias, tumors in the abdomen or intestines; inflammatory bowel disease; bowel obstruction; lung disease, especially pneumonia; bacterial blood poisoning; very high blood fat levels; uremia that cannot be treated with peritoneal dialysis; or severe malnutrition and weight loss, especially if adequate protein intake is not possible.
- Inform your doctor immediately if you have an overactive parathyroid gland; very low blood calcium levels; severe electrolyte imbalance due to vomiting or diarrhea; abnormal kidneys (polycystic kidneys); peritonitis (signs include cloudy dialysate, abdominal pain, fever, malaise, or blood poisoning – show the drained fluid bag to your doctor); or severe abdominal pain, distension, or vomiting (signs of encapsulating peritoneal sclerosis, which can be life-threatening).
- Peritoneal dialysis can lead to the loss of proteins and water-soluble vitamins; a good diet or nutritional supplements are recommended to prevent deficiencies. Due to its high glucose concentration, balance 4.25% glucose, 1.25 mmol/l calcium should be used with caution and under medical supervision.
- If you use too much of the medicine, or if a child accidentally takes it, always contact a doctor, hospital, or a Poison Information Centre immediately. If dialysate changes have been too frequent, contact your doctor due to risk of dehydration or electrolyte imbalance. If you forget to change the dialysate or use too little solution, try to complete the prescribed daily amount (for 24 hours) to avoid life-threatening consequences. If unsure, contact your treating doctor.