Zyloric
Zyloric is a medicine that helps lower uric acid levels in your body, used to treat gout and prevent kidney stones.
Form
tabletti
Strength
100 mg
Active Ingredient
Allopurinol
Manufacturer
Aspen Pharma Trading Limited
How to Use
Dosage
Your doctor will decide your dose, usually between 100 mg and 900 mg per day. For children under 15, the usual dose is 100-400 mg daily.
Method
Take Zyloric after food and swallow it with a glass of water.
Important
The maximum daily dose is usually 900 mg, but your doctor may adjust this.
Possible Side Effects
COMMON
- •Skin rash
RARE
- •Nausea or vomiting
- •Diarrhea
- •Liver problems, such as hepatitis, or abnormal liver tests
- •Fever, chills, headache, muscle pain (flu-like symptoms), and general malaise
- •Severe allergic reactions affecting many organs, with symptoms like fever, rash, joint pain, and changes in blood and liver values
- •Skin changes such as sores in the mouth, throat, nose, genitals, red and swollen eyes (conjunctivitis), widespread blistering, or skin peeling
- •Bleeding from lips, eyes, mouth, nose, or genitals
- •Blood problems, which may cause easy bruising, sore throat, or other signs of infection
- •Swollen lymph glands
- •High body temperature
- •Blood in urine (hematuria)
- •High blood cholesterol levels (hyperlipidemia)
- •General weakness or feeling unwell
- •Weakness in legs, numbness, unsteadiness, inability to move muscles (paralysis), or loss of consciousness
- •Headache, dizziness, lightheadedness, or vision problems
- •Chest pain (angina pectoris), high blood pressure, or slow pulse
- •Male infertility or erectile dysfunction
- •Breast enlargement in men and women
- •Changes in bowel habits
- •Taste changes
- •Cataracts (clouding of the eye lens)
- •Hair loss or discoloration
- •Depression
- •Loss of voluntary muscle coordination (ataxia)
- •Tingling, prickling, or burning sensation on the skin (paresthesia)
- •Fluid retention causing swelling (edema), especially in the ankles
- •Abnormal glucose metabolism (diabetes); your doctor may check your blood sugar levels
- •Inflammation of the membranes surrounding the brain and spinal cord (aseptic meningitis), with symptoms like stiff neck, headache, nausea, fever, or confusion (seek immediate medical attention)
- •Lichenoid rash (itchy, red-purple rash and/or thread-like whitish-grey lines on mucous membranes)
Important Warnings
- Do not take Zyloric if you are allergic to allopurinol or any other ingredient in the medicine.
- Stop taking Zyloric and contact your doctor immediately if you develop a severe skin rash with fever, sores in your mouth, eyes, or genitals, or if your skin peels.
- Tell your doctor if you have liver or kidney problems, heart problems, high blood pressure (especially if taking diuretics or ACE inhibitors), or thyroid problems.
- If you are of Han-Chinese, Thai, or Korean origin, you may have a higher risk of serious skin reactions. Discuss this with your doctor.
- If you are pregnant, breastfeeding, or planning to have a baby, ask your doctor for advice before taking this medicine. Zyloric is not recommended during breastfeeding.
Show 3 more warnings
- This medicine may cause dizziness, drowsiness, or coordination problems. Do not drive or operate machinery if you experience these symptoms.
- Avoid taking Zyloric with 6-mercaptopurine or azathioprine; if you must, your doctor will adjust the dose and monitor your blood closely due to an increased risk of severe blood disorders.
- If you are taking aluminium hydroxide, take Zyloric at least three hours apart to ensure it works effectively.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Reduce the dose already in mild renal impairment. Consider potential interactions. (updated 16.9.2024)