Zoledronic acid Stada
Zoledronic acid Stada helps prevent bone damage and high calcium levels in the blood for cancer patients.
Form
infuusioneste, liuos
Strength
4 mg / 100 ml
Active Ingredient
Zoledronic acid monohydrate
Manufacturer
STADA Arzneimittel AG
How to Use
Dosage
The usual dose is 4 mg.
Method
This medicine is given as an infusion (drip) directly into a vein by a healthcare professional in a hospital or clinic. The infusion takes at least 15 minutes.
Important
One infusion is typically given every three to four weeks to prevent bone damage. If your calcium levels are too high, you usually receive only one infusion.
Possible Side Effects
COMMON
- •Low phosphate levels in blood.
- •Severe kidney problems (seen in blood tests).
- •Low blood calcium levels.
- •Headache and flu-like symptoms, including fever, tiredness, weakness, drowsiness, chills, and bone, joint, and/or muscle pain.
- •Stomach problems like nausea, vomiting, and loss of appetite.
- •Eye inflammation (conjunctivitis).
- •Low red blood cell count (anemia).
RARE
- •Pain in the mouth, teeth, and/or jaw, swelling or sores in the mouth or jaw that won't heal, discharge, numbness or a feeling of heaviness in the jaw, or loose teeth. These can be signs of jaw bone damage (osteonecrosis).
- •Irregular heartbeat (atrial fibrillation), mainly in postmenopausal women treated for osteoporosis.
- •Severe allergic reactions like trouble breathing, swelling mainly in the face and throat.
- •Irregular heartbeats due to low calcium levels.
- •A kidney disorder called Fanconi syndrome.
- •Seizures, numbness, and muscle twitching due to low calcium levels.
- •Ear pain, ear infection, and/or discharge from the ear, which can be signs of ear bone damage.
- •Bone damage (osteonecrosis) in other bones, especially the hip or thigh bone.
- •Kidney inflammation (tubulointerstitial nephritis), with symptoms like reduced urine, blood in urine, nausea, or general discomfort.
- •Allergic reactions.
- •Low blood pressure.
- •Chest pain.
- •Skin reactions at the injection site (redness, swelling), rash, itching.
- •High blood pressure, shortness of breath, dizziness, anxiety, sleep problems, taste changes, tremors, tingling or numbness in hands and feet, diarrhea, constipation, stomach pain, dry mouth.
- •Low white blood cell and platelet counts.
- •Low magnesium and potassium levels in blood.
- •Weight gain.
- •Increased sweating.
- •Drowsiness.
- •Blurred vision, watery eyes, sensitivity to light.
- •Sudden chills with fainting, weakness, or collapse.
- •Difficulty breathing with wheezing or coughing.
- •Hives.
- •Slow heartbeat.
- •Confusion.
- •Unusual thigh bone fractures (especially in patients on long-term osteoporosis treatment).
- •Lung disease (inflammation in the tissue around the air sacs).
- •Flu-like symptoms, including joint inflammation and swelling.
- •Painful redness and/or swelling in the eye.
- •Fainting due to low blood pressure.
- •Severe bone, joint, and/or muscle pain, sometimes disabling.
Important Warnings
- Do not use if you are breastfeeding.
- Do not use if you are allergic to zoledronic acid, other similar medicines (bisphosphonates), or any other ingredient in this medicine.
- Tell your doctor if you have or have had kidney problems.
- Tell your doctor and dentist if you have jaw pain, swelling, numbness, a heavy feeling in your jaw, loose teeth, or are planning dental surgery. These can be signs of jaw bone damage.
- If you experience muscle cramps, dry skin, burning sensation, irregular heartbeat, seizures, or muscle twitching, tell your doctor right away. You may need calcium and vitamin D supplements.