Zoledronic Acid Fresenius Kabi
This medicine slows down bone breakdown and is used to prevent bone damage in cancer patients and to lower high calcium levels in the blood.
Form
infuusiokonsentraatti, liuosta varten
Strength
4 mg / 5 ml
Active Ingredient
Zoledronic acid monohydrate
Manufacturer
Fresenius Kabi AB
How to Use
Dosage
4 mg as a single dose.
Method
Given as a 20-minute infusion directly into a vein.
Important
Typically one infusion per treatment session, not daily.
Possible Side Effects
COMMON
- •Low phosphate levels in the blood.
- •Headache and flu-like symptoms, including fever, tiredness, weakness, chills, and bone, joint, or muscle pain.
- •Stomach problems like nausea, vomiting, and loss of appetite.
- •Eye inflammation (conjunctivitis).
- •Low red blood cell count (anemia).
RARE
- •Allergic reactions.
- •Low blood pressure.
- •Chest pain.
- •Skin reactions (redness, swelling) at the infusion site, rash, itching.
- •High blood pressure.
- •Shortness of breath.
- •Dizziness.
- •Anxiety.
- •Sleep problems.
- •Taste changes.
- •Tremors.
- •Tingling or numbness in hands and feet.
- •Diarrhea.
- •Constipation.
- •Stomach pain.
- •Dry mouth.
- •Low white blood cell and platelet counts.
- •Low magnesium and potassium levels in the blood.
- •Weight gain.
- •Increased sweating.
- •Drowsiness.
- •Blurred vision, watery eyes, sensitivity to light.
- •Sudden coldness with fainting, weakness, or loss of consciousness.
- •Shortness of breath with wheezing or coughing.
- •Hives.
- •Slow heart rate.
- •Confusion.
- •Rare thigh bone fractures, especially with long-term osteoporosis treatment. Contact your doctor if you have pain or weakness in your thigh, hip, or groin.
- •Lung disease (inflammation in the tissue around the air sacs).
- •Flu-like symptoms, including joint inflammation and swelling.
- •Painful red and/or swollen eyes.
- •Fainting due to low blood pressure.
- •Severe bone, joint, and/or muscle pain, sometimes disabling.
- •Kidney inflammation (tubulointerstitial nephritis): symptoms include reduced urine output, blood in urine, nausea, and general unwellness.
Important Warnings
- Do not take if you are allergic to zoledronic acid, other bisphosphonates, or any other ingredients in this medicine.
- Do not take if you are breastfeeding.
- Do not take if you are pregnant or suspect you are pregnant.
- Tell your doctor if you have or have had kidney problems.
- Inform your doctor immediately if you experience pain, swelling, or numbness in your jaw, or a feeling of heavy jaw, or if a tooth has fallen out, as these can be signs of jaw bone damage.
Show 2 more warnings
- Your doctor will check your blood with tests before and during treatment.
- This medicine can cause low calcium levels in the blood. You may need calcium and vitamin D supplements. Report any muscle cramps, dry skin, burning sensations, irregular heartbeat, or seizures to your doctor immediately.