Zoladex
Zoladex is a medicine that reduces the levels of certain natural hormones in the body, such as testosterone in men and estrogen in women, used to treat conditions like prostate cancer, endometriosis, and breast cancer.
Form
implantaatti
Strength
3.6 mg
Active Ingredient
Goserelin acetate
Manufacturer
AstraZeneca Oy
How to Use
Dosage
One implant.
Method
A doctor or nurse places the implant under the skin of your belly.
Important
The treatment is repeated every 28 days; for women, endometriosis treatment lasts up to six months, and myoma treatment up to three months.
Possible Side Effects
COMMON
- •Changes in how much you want sex.
- •Feeling sudden warmth (hot flashes) and sweating a lot.
- •Pain, bruising, or bleeding where the implant was placed.
- •Changes in mood or feeling sad and down.
- •Tingling, prickling, or numbness in your skin.
- •Changes in your blood pressure.
- •Skin rash.
- •Pain in your joints.
- •Bones becoming less strong.
- •Gaining weight.
- •Hair loss.
- •Trouble getting or keeping an erection (for men).
- •Lower blood sugar levels (for men).
- •Pressure on the spinal cord (for men).
- •Serious heart problems, such as heart failure or heart attack (for men).
- •Bone pain (for men).
- •Swelling of the breasts (for men).
- •Vaginal dryness (for women).
- •Changes in breast size (for women).
- •Acne (for women).
- •Headache (for women).
RARE
- •Allergic reactions.
- •A very severe allergic reaction that can be life-threatening.
- •A growth on the pituitary gland (a gland in the brain) that can cause severe headaches, vision loss, or passing out.
- •Mental health issues, such as seeing or hearing things that are not real.
- •Changes in your heart's electrical activity, seen on an ECG test.
- •A blockage in the tube that carries urine from the kidney to the bladder (for men).
- •Soreness or tenderness in the breasts (for men).
- •Too much calcium in the blood (for women).
- •An ovarian cyst (a fluid-filled sac on an ovary, for women).
- •Ovaries that are too active (for women, especially with fertility treatment).
- •Bleeding that occurs when hormone levels drop (for women).
- •Uterine fibroids (myomas) getting smaller or breaking down (for women).
Important Warnings
- Do not use Zoladex if you are allergic to goserelin or any other ingredient in Zoladex.
- This medicine can weaken your bones. Tell your doctor if you have any condition that affects bone strength.
- Zoladex should not be given to children.
- If you are hospitalized, tell the healthcare staff that you are receiving Zoladex treatment.
- Do not stop using Zoladex unless your doctor tells you to.
Show 5 more warnings
- Talk to your doctor if you have heart or blood vessel disease, like an irregular heartbeat, or if you take medicines for it, as Zoladex may increase the risk of heart rhythm problems.
- Depression, which can be severe, has been reported in patients taking Zoladex. Tell your doctor if you become depressed during Zoladex treatment.
- Men should talk to their doctor before treatment if they have had trouble urinating, lower back pain, or diabetes.
- Women should use condoms or an IUD for contraception during Zoladex treatment, unless for fertility treatment. Do not use birth control pills.
- Do not use Zoladex if you are pregnant or trying to become pregnant (unless for fertility treatment). If you become pregnant during treatment, tell your doctor immediately. Do not use Zoladex while breastfeeding.