Zofran
Zofran is a medicine used to prevent nausea and vomiting caused by cancer treatment or surgery.
Form
tabletti, kalvopäällysteinen
Strength
8 mg
Active Ingredient
Ondansetron hydrochloride dihydrate
Manufacturer
Sandoz A/S
How to Use
Dosage
For adults, the typical dose is 4-8 mg, taken 1-2 hours before cancer treatment or surgery. Additional doses of 8 mg may be taken 12 hours later or twice daily for up to 5 days, as prescribed by your doctor.
Method
Swallow the tablet whole with a glass of water.
Important
For adults, the maximum daily dose is typically 16 mg. For children, the maximum daily dose is 8 mg.
Possible Side Effects
COMMON
- •Headache
- •Feeling of warmth or flushing
- •Constipation
RARE
- •Seizures
- •Movement disorders
- •Irregular heartbeat or slow heart rate
- •Chest pain
- •Low blood pressure
- •Hiccups
- •Heart rhythm problems (sometimes causing sudden loss of consciousness)
- •Temporary blurred vision or other vision disturbances
- •Temporary vision loss
- •Widespread blistering rash and peeling skin (toxic epidermal necrolysis)
- •Raised, itchy rash (hives)
- •Swelling, sometimes of the face and mouth area (angioedema), causing breathing difficulties or loss of consciousness.
- •Sudden chest pain or a tight feeling in the chest.
Important Warnings
- Do not take Zofran if you are using apomorphine (a medicine for Parkinson's disease).
- Do not take Zofran if you are allergic to ondansetron or any other ingredient in this medicine.
- Talk to your doctor if you are allergic to similar medicines like granisetron or palonosetron.
- Talk to your doctor if you have had heart problems, such as an irregular heartbeat.
- Talk to your doctor if you have bowel problems.
Show 4 more warnings
- Talk to your doctor if you have liver disease, as your doctor may need to lower your dose.
- Do not use Zofran during the first three months of pregnancy, as it may slightly increase the risk of a baby being born with a cleft lip and/or palate.
- Do not breastfeed while taking Zofran, as the medicine can pass into breast milk and affect your baby.
- Seek immediate medical attention if you experience sudden chest pain or a tight feeling in your chest.
Use in Elderly Patients
Category C
Suitable for older adults, with specific cautions. May prolong the QT interval especially with other preparations prolonging QT. Take interactions into account. (updated 20.5.2024)