Zofran
Zofran is a medicine that helps prevent feeling sick and throwing up after cancer treatment or surgery.
Form
tabletti, kalvopäällysteinen
Strength
4 mg
Active Ingredient
Ondansetron hydrochloride dihydrate
Manufacturer
Sandoz A/S
How to Use
Dosage
Your doctor will tell you how much to take; usually 8 mg before treatment or surgery, and again if needed.
Method
Swallow the tablet whole with a glass of water.
Important
For adults, the maximum dose is usually 16 mg per day; a child's dose is set by the doctor.
Possible Side Effects
COMMON
- •Headache
- •Feeling of warmth or flushing
- •Constipation
RARE
- •Seizures
- •Movement disorders
- •Irregular or slow heartbeat
- •Chest pain
- •Low blood pressure
- •Hiccups
- •Higher liver enzyme values (without symptoms, seen in blood tests)
- •Dizziness (especially with fast IV injection)
- •Temporary blurred vision or visual disturbances
- •Heart rhythm disorders (sometimes causing sudden loss of consciousness)
- •Temporary loss of vision
- •Widespread blistering rash and skin peeling (toxic epidermal necrolysis)
- •Raised and itchy rash (hives)
- •Swelling of face/mouth (angioedema)
- •Difficulty breathing or loss of consciousness due to swelling
- •Sudden chest pain or tightness in the chest
Important Warnings
- Do not use Zofran if you are taking apomorphine (a medicine for Parkinson's disease).
- Tell your doctor if you are allergic to ondansetron or similar medicines.
- Tell your doctor if you have had heart problems, like an irregular heartbeat.
- Tell your doctor if you have bowel problems or liver disease.
- Get medical help right away if you feel sudden chest pain or tightness in your chest during or after treatment.
Show 1 more warnings
- Not recommended during the first three months of pregnancy or while breastfeeding.
Use in Elderly Patients
Category C
Suitable for older adults, with specific cautions. May prolong the QT interval especially with other preparations prolonging QT. Take interactions into account. (updated 20.5.2024)