Zeldox
Zeldox is an antipsychotic medicine used to quickly calm agitation (restlessness) in adults with schizophrenia.
Form
injektiokuiva-aine, liuosta varten
Strength
20 mg/ml
Active Ingredient
Ziprasidone mesylate trihydrate
Manufacturer
Upjohn EESV
How to Use
Dosage
The recommended dose is 10 mg, but sometimes a 20 mg dose may be needed as the first dose.
Method
Zeldox is given as an injection into a muscle. If your first dose is 10 mg, you can get a second injection two hours later. If your first dose is 20 mg, you can get a second injection four hours later. It must not be injected into a blood vessel.
Important
Zeldox injections can be given for a maximum of three consecutive days.
Possible Side Effects
COMMON
- •trouble sleeping
- •agitation or anxiety
- •restlessness
- •movement disorders, including muscle stiffness, slow movements, and shaking
- •drowsiness
- •headache
- •dizziness
- •high blood pressure
- •low blood pressure
- •nausea, vomiting
- •constipation
- •dry mouth
- •feeling weak or powerless
- •burning sensation and/or pain at the injection site
- •increased tiredness
RARE
- •decreased appetite
- •difficulty with social interactions, seeing or hearing things that are not there
- •mania (extreme energy, unusual thoughts, and hyperactivity)
- •difficulty controlling movements or making involuntary sounds like clearing the throat, sniffing, or grunting; difficulty or inability to move certain body parts; clumsiness
- •loss of consciousness
- •speech disorder
- •slow heart rate
- •loss of balance, vertigo
- •flushing sensation
- •stomach problems, such as diarrhea
- •increased or excessive sweating
- •rash
- •flu-like illness
- •discomfort and redness at the injection site
- •withdrawal symptoms caused by the medicine
- •increase in liver enzyme levels
- •urinary incontinence, painful urination, or difficulty urinating
- •fast or irregular heartbeat, dizziness when standing up, which may indicate abnormal heart function, possibly related to postural hypotension
- •involuntary or unusual movements, especially of the face or tongue
- •prolonged, abnormal, and painful erection of the penis (priapism)
- •swelling of the face, lips, tongue, or throat; difficulty swallowing or breathing; hives. These may be signs of a severe allergic reaction like angioedema.
- •fever, rapid breathing, sweating, muscle stiffness, shaking, difficulty swallowing, and reduced consciousness. These may be signs of neuroleptic malignant syndrome.
- •skin reactions, especially rash, fever, and swollen lymph nodes, which may be symptoms of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS). These reactions can be life-threatening.
- •confusion, agitation, high temperature, sweating, lack of muscle coordination, muscle twitching. These may be signs of serotonin syndrome.
- •rapid, irregular heartbeat and fainting, which may be signs of a life-threatening condition called Torsades de Pointes.
- •facial paralysis
- •blood clots, especially in the leg veins (symptoms include swelling, pain, and redness in the legs), which can travel to the lungs, causing chest pain and breathing difficulties. Seek medical attention immediately if you experience these symptoms.
- •involuntary urination
- •withdrawal symptoms in newborns caused by the medicine
- •abnormal breast milk production
Important Warnings
- Do not use Zeldox if you are allergic to ziprasidone or any other ingredients. Signs of an allergic reaction include rash, itching, swelling of the face or lips, and trouble breathing.
- Do not use Zeldox if you have or have had heart problems or a recent heart attack, or if you take medicines that affect your heart rhythm.
- Tell your doctor if you or anyone in your family has had blood clots, as medicines like Zeldox can be linked to their formation.
- Tell your doctor if you have liver problems.
- Tell your doctor if you have or have had seizures or epilepsy.
Show 9 more warnings
- Be careful if you are over 65 years old and have dementia, as there is an increased risk of stroke.
- Tell your doctor if you have a slow resting heart rate or a salt imbalance from severe diarrhea, vomiting, or using diuretics.
- Contact your doctor immediately if you experience a fast or irregular heartbeat, weakness, fainting, or dizziness when standing up.
- Contact your doctor immediately if you experience severe skin reactions like blistering rash, mouth sores, peeling skin, fever, or target-like patches, as these can be life-threatening.
- Zeldox injections can cause drowsiness, low blood pressure when standing up, dizziness, and walking problems, which can lead to falls, especially in older or frail patients.
- Do not use Zeldox during pregnancy unless prescribed by your doctor, as it may harm the baby. If used in the last 3 months of pregnancy, the baby may have symptoms like shaking, stiff or weak muscles, drowsiness, agitation, breathing problems, or feeding difficulties. Contact your doctor if your baby shows these symptoms.
- Do not breastfeed while taking Zeldox, as small amounts of the medicine may pass into breast milk.
- Zeldox can make you feel drowsy. Do not drive or operate machines until the drowsiness has passed.
- Do not drink alcohol while taking Zeldox, as it increases the risk of side effects.