Zanipress
Zanipress is a medicine with two active ingredients (enalapril and lercanidipine) that work together to lower high blood pressure in adults when enalapril alone isn't enough.
Form
tabletti, kalvopäällysteinen
Strength
20 mg / 10 mg
Active Ingredient
Lercanidipine hydrochloride
Manufacturer
Recordati Ireland Ltd.
How to Use
Dosage
One tablet.
Method
Take one tablet by mouth once a day, preferably in the morning at least 15 minutes before breakfast. Swallow the tablet whole with water.
Important
One tablet per day.
Possible Side Effects
COMMON
- •Cough
- •Dizziness, headache
RARE
- •Changes in blood tests (like fewer blood cells or platelets)
- •Increased potassium in the blood
- •Feeling nervous or anxious
- •Dizziness when standing up, feeling lightheaded or fainting
- •Fast or irregular heartbeat
- •Sudden redness of face, neck or upper chest; low blood pressure
- •Stomach pain, constipation, nausea, diarrhea, dry mouth, swollen gums, salty taste in mouth
- •Increased liver enzyme levels
- •Skin redness, rash, hives, swelling of skin (angioedema)
- •Joint pain
- •Increased need to urinate, frequent urination at night
- •Feeling weak, tired, hot flushes, swollen ankles
- •Ringing in the ears (tinnitus)
- •Dry or sore throat
- •Impotence
Important Warnings
- Do not take if you are allergic to enalapril, lercanidipine, or any other ingredient in this medicine.
- Do not take if you have ever had swelling of your face, lips, mouth, tongue, or throat (angioedema) after taking an ACE inhibitor, or if you have hereditary angioedema.
- Do not take if you are taking or have recently taken sacubitril/valsartan (for heart failure).
- Do not take if you have diabetes or kidney problems AND are taking a blood pressure medicine containing aliskiren.
- Do not take if you are more than 3 months pregnant or planning to become pregnant (use should also be avoided in early pregnancy).
Show 4 more warnings
- Do not take if you have certain serious heart conditions (e.g., obstruction to blood flow from the heart, uncontrolled heart failure, unstable angina pectoris, or a heart attack within the last month).
- Do not take if you have severe liver or kidney problems, or are on dialysis.
- Do not take if you are using medicines that slow down liver function (e.g., certain antifungals, antibiotics, antivirals), or cyclosporine.
- Do not take if you consume grapefruit or grapefruit juice.
Use in Elderly Patients
Category A
Suitable for older adults. Do not use in severe renal impairment. Significant adverse effects include ankle oedema and orthostatic hypotension. Consider potential interactions. Avoid grapefruit. (updated 17.2.2025)