Xilmac
Xilmac is an antibiotic used to kill bacteria causing various infections and to prevent infections during major surgeries in adults and children.
Form
injektio-/infuusiokuiva-aine liuosta varten
Strength
1000 mg / 200 mg
Active Ingredient
Amoxicillin sodium
Manufacturer
Macure Pharma ApS
How to Use
Dosage
For adults and children weighing 40 kg or more: 1000 mg/200 mg every 8 hours. For children under 40 kg: 25 mg/5 mg per kg body weight every 8 hours (3 months or older) or every 12 hours (under 3 months or under 4 kg).
Method
This medicine is given as an injection into a vein or as an intravenous infusion by a healthcare professional. Drink plenty of fluids during treatment.
Important
The dose is administered according to the specified intervals, typically every 8 or 12 hours depending on age and weight.
Possible Side Effects
COMMON
- •Yeast infection (candida) of the vagina, mouth, or skin folds.
- •Diarrhoea.
RARE
- •Rash, itching.
- •Itchy raised rash (hives).
- •Nausea, especially with high doses.
- •Vomiting.
- •Indigestion.
- •Dizziness.
- •Headache.
- •Increase in some liver enzymes (seen in blood tests).
- •Rash with blisters that look like small targets (erythema multiforme). If you notice these symptoms, contact a doctor immediately.
- •Swelling, redness, and tenderness along a vein.
- •Low number of cells involved in blood clotting (platelets) (seen in blood tests).
- •Low number of white blood cells (seen in blood tests).
- •Rash.
- •Inflammation of blood vessels (vasculitis), which may appear as red or purple raised spots on the skin, but can affect other parts of the body.
- •Fever, joint pain, swollen glands in the neck, armpit, or groin.
- •Swelling, sometimes of the face or throat (angioedema), causing difficulty breathing.
- •Collapse.
- •Chest pain in the context of an allergic reaction, which can be a symptom of allergy-induced heart attack (Kounis syndrome).
- •Inflammation of the large intestine (colitis) causing watery diarrhoea (often with blood and mucus), stomach pain, and/or fever.
- •Acute inflammation of the pancreas (pancreatitis). If you have severe and persistent pain in the stomach area, this could be a sign of acute pancreatitis.
- •Drug-induced enterocolitis syndrome (DIES), mainly reported in children. Main symptom is repeated vomiting (1-4 hours after administration). Other symptoms can include stomach pain, severe tiredness, diarrhoea, and low blood pressure.
- •Inflammation of the protective membranes surrounding the brain (aseptic meningitis).
- •Widespread rash with blisters and peeling skin, especially around the mouth, nose, eyes, and genitals (Stevens-Johnson syndrome), or a more severe form with extensive peeling of the skin (toxic epidermal necrolysis).
- •Widespread red rash with small pus-filled blisters (bullous exfoliative dermatitis).
- •Red, scaly rash with bumps under the skin and blisters (exanthematous pustulosis).
- •Flu-like symptoms with rash, fever, swollen glands, and abnormal blood test results (DRESS syndrome).
- •Liver inflammation (hepatitis).
- •Yellowing of the skin and whites of the eyes (jaundice) due to increased bilirubin in the blood.
- •Inflammation of kidney tubules (interstitial nephritis).
- •Slower blood clotting.
- •Seizures (convulsions), especially in patients taking high doses of amoxicillin/clavulanic acid or those with kidney problems.
- •Blistering rash that forms a circle with a crusty center or appears like a string of pearls (linear IgA disease).
- •Severe decrease in white blood cells, low red blood cells (hemolytic anemia), and crystals in the urine leading to acute kidney injury (seen in blood/urine tests).
Important Warnings
- Do not take if you are allergic to amoxicillin, clavulanic acid, penicillin, or any other ingredients in Xilmac.
- Do not take if you have had a severe allergic reaction to another antibiotic, which could include a rash or swelling of the face or throat.
- Do not take if you have experienced liver problems or jaundice (yellowing of the skin) when previously taking an antibiotic.
- Tell your doctor if you have glandular fever (mononucleosis).
- Tell your doctor if you are being treated for kidney or liver problems.
Show 1 more warnings
- Tell your doctor if you are not urinating regularly.