Wilfactin
WILFACTIN is a medicine made from human plasma that replaces missing von Willebrand factor to help blood clot in patients with von Willebrand disease and to prevent or treat bleeding.
Form
injektiokuiva-aine ja liuotin, liuosta varten
Strength
100 IU/ml
Active Ingredient
Human von Willebrand factor
Manufacturer
LFB Biomedicaments
How to Use
Dosage
Typically 40-80 IU/kg, adjusted by a doctor based on your condition. For long-term prevention, 40-60 IU/kg two to three times a week. Children under 6 may need up to 100 IU/kg.
Method
Administered as an intravenous injection.
Important
Your doctor will determine the maximum daily dose for you to ensure safety and prevent blood clots.
Possible Side Effects
COMMON
- •Infusion site reactions
RARE
- •Dizziness
- •Reduced sensation
- •Redness
- •Itching
- •Pressure sensation
- •Chills or shivering
- •Difficulty breathing or swallowing
- •Wheezing
- •Chest tightness
- •Rapid heart rate
- •Drop in blood pressure
- •Fainting
- •Severe fatigue
- •Restlessness or nervousness
- •Headache
- •Skin redness or hot flashes
- •Swelling in various parts of the body
- •Rash or generalized hives
- •Warmth and tingling at the infusion site
- •Tingling
- •Vomiting
- •Nausea
- •Fever
Important Warnings
- Do not use if you are allergic to human von Willebrand factor or any other ingredients in WILFACTIN, or if you have hemophilia A.
- Treatment must always be supervised by a doctor experienced in treating bleeding disorders.
- There is a risk of blood clots (thrombosis), especially if you have known risk factors; your doctor will monitor you closely for early signs and may start preventive treatment.
- Severe allergic reactions (hypersensitivity, anaphylaxis) can occur. If you experience any signs of an allergic reaction (e.g., difficulty breathing, rash, chest tightness), stop treatment immediately and seek medical help.
- Because this medicine is made from human blood, there is a small risk of virus transmission. Your doctor may recommend hepatitis A and B vaccinations if you use WILFACTIN regularly.
Show 2 more warnings
- In some patients with von Willebrand disease, especially type 3, the body may develop inhibitors that make the medicine less effective. Your doctor will monitor you for this.
- Use during pregnancy and breastfeeding only if clearly necessary; consult your doctor or pharmacist before using this medicine.