Voxra
Voxra is a medicine used to treat depression by affecting certain chemicals in your brain called noradrenaline and dopamine.
Form
säädellysti vapauttava tabletti
Strength
150 mg
Active Ingredient
Bupropion hydrochloride
Manufacturer
GlaxoSmithKline Oy
How to Use
Dosage
The usual dose for adults is one 150 mg tablet once daily. Your doctor might increase it to 300 mg once daily if your depression doesn't improve.
Method
Swallow the tablets whole in the morning. Do not chew, crush, or divide them.
Important
Do not take Voxra more than once a day. The maximum daily dose is 300 mg.
Possible Side Effects
COMMON
- •Sleep problems (take Voxra in the morning)
- •Headache
- •Dry mouth
- •Nausea, vomiting
- •Fever
- •Dizziness
- •Itching, sweating, and skin rash (sometimes due to an allergic reaction)
- •Tremors, shaking
- •Weakness, tiredness
- •Chest pain
- •Anxiety or irritability
- •Stomach pain or other stomach issues (such as constipation)
- •Taste changes
- •Loss of appetite
- •Increased blood pressure (sometimes severe), flushing
- •Ringing in the ears
- •Vision problems
RARE
- •Seizures
- •Worsening depression or suicidal thoughts (talk to your doctor immediately)
- •Feeling confused
- •Difficulty concentrating
- •Fast heartbeat
- •Weight loss
- •Heart palpitations, fainting
- •Muscle twitching, stiffness, uncontrolled movements, problems with walking or coordination
- •Restlessness, irritability, hostility, aggressiveness, unusual dreams, numbness or tingling, memory loss
- •Yellowing of skin or whites of eyes (due to high liver enzyme levels, liver inflammation)
- •Severe allergic reactions, rash with joint and muscle pain
- •Blood sugar changes
- •Increased or decreased urge to urinate
- •Urinary incontinence (uncontrolled urination)
- •Severe rash in mouth or other body parts that can be life-threatening
- •Worsening of psoriasis (red, thickened skin patches)
- •Unusual hair loss or thinning (alopecia)
- •Feeling unreal or strange, hallucinations, delusions, strong paranoia
- •Suicidal thoughts (contact your doctor or go to a hospital immediately)
- •Losing touch with reality, inability to think clearly (psychosis); other symptoms might include hallucinations or delusions
- •Sudden and intense fear (panic attack)
- •Stuttering
- •Decreased red blood cells (anemia), white blood cells (leukopenia), and platelets (thrombocytopenia)
- •Low sodium levels in the blood (hyponatremia)
- •Mental state changes (like agitation, hallucinations, coma) and other effects (fever over 38°C, fast heart rate, unstable blood pressure, overactive reflexes, muscle stiffness, lack of coordination, and/or stomach problems like nausea, vomiting, diarrhea) when Voxra is taken with other antidepressants.
Important Warnings
- Do not take Voxra if you are allergic to bupropion or any other ingredient in this medicine.
- Do not take Voxra if you are already taking other medicines that contain bupropion.
- Do not take Voxra if you have been diagnosed with epilepsy or have a history of seizures.
- Do not take Voxra if you have or have had an eating disorder like bulimia or anorexia.
- Do not take Voxra if you have a brain tumor.
Show 6 more warnings
- Do not take Voxra if you regularly drink a lot of alcohol and have recently stopped or plan to stop drinking.
- Do not take Voxra if you have severe liver problems.
- Do not take Voxra if you have recently stopped taking sedatives or plan to stop taking them while on Voxra.
- Do not take Voxra if you are taking or have taken other antidepressants called MAOIs in the last 14 days.
- Do not use Voxra if you are pregnant, think you might be pregnant, or are breastfeeding, unless your doctor says it's necessary.
- If Voxra makes you feel confused or dizzy, do not drive or operate machinery.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Consider risk of convulsions and numerous potential interactions. Reduce the dose already in mild renal impairment. Increases risk of falls. (updated 12.2.2024)