Vortioxetine Krka
Vortioxetine Krka is a medicine containing vortioxetine, used to treat major depression in adults by helping to relieve symptoms like sadness, anxiety, and sleep problems.
Form
tabletti, kalvopäällysteinen
Strength
20 mg
Active Ingredient
Vortioxetine hydrobromide
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
For adults under 65, the usual dose is 10 mg once a day. Your doctor might adjust it between 5 mg and 20 mg daily. If you are 65 or older, the starting dose is 5 mg once a day.
Method
Swallow the tablet whole with a glass of water. You can take it with or without food.
Important
The highest daily dose is 20 mg.
Possible Side Effects
COMMON
- •Nausea
- •Diarrhea
- •Constipation
- •Vomiting
- •Dizziness
- •Itching all over the body
- •Unusual dreams
- •Increased sweating
- •Indigestion
RARE
- •Redness
- •Night sweats
- •Blurred vision
- •Involuntary tremors
- •Hallucinations (seeing, hearing, or feeling things that are not there)
- •Dilated pupils (mydriasis), which may increase the risk of glaucoma.
- •Low sodium in the blood (symptoms may include dizziness, weakness, confusion, drowsiness, severe tiredness, nausea, vomiting; more serious symptoms include fainting, seizures, or falls).
- •Serotonin syndrome (see warnings).
- •Severe allergic reactions (e.g., swelling of face/lips/tongue/throat, difficulty breathing/swallowing, sudden drop in blood pressure).
- •Hives
- •Excessive or unexplained bleeding (including bruising, nosebleeds, and bleeding from the stomach/intestines or vagina).
- •Rash
- •Sleep disturbances (insomnia)
- •Agitation and aggression.
- •Headache
- •Increased levels of a hormone called prolactin in the blood.
- •Inability to sit still (akathisia)
- •Teeth grinding (bruxism)
- •Inability to open mouth (trismus)
- •Restless legs syndrome (an urge to move legs to stop unpleasant sensations, often at night).
- •Abnormal milk secretion from the breast (galactorrhea).
- •Increased risk of bone fractures.
- •Increased risk of sexual dysfunction.
Important Warnings
- Do not take if you are allergic to vortioxetine or any other ingredient in this medicine.
- Do not take if you are currently using certain other antidepressants called MAO inhibitors.
- Tell your doctor if you take other medicines that affect serotonin (e.g., strong pain relievers, migraine medicines ending in "-triptan"), as this may increase the risk of serotonin syndrome (symptoms like hallucinations, fast heartbeat, high blood pressure, fever, nausea, and diarrhea).
- Discuss with your doctor if you have a history of seizures or have unstable epilepsy.
- Tell your doctor if you have had mania.
Show 11 more warnings
- Inform your doctor if you bleed or bruise easily, or if you are pregnant, as this medicine can increase the risk of bleeding.
- Tell your doctor if you have low sodium levels in your blood.
- If you are 65 years old or older, discuss your dosage with your doctor.
- Inform your doctor if you have severe kidney or liver disease.
- Tell your doctor if you have or have had high eye pressure (glaucoma) or blurred vision during treatment.
- Contact your doctor if you experience feelings of aggression, agitation, anger, or irritability while taking this medicine.
- This medicine can increase thoughts of self-harm or suicide, especially in young adults; seek medical help immediately if this happens.
- Vortioxetine Krka is not recommended for children and adolescents under 18 years of age.
- Avoid alcohol while taking this medicine.
- Do not use during pregnancy unless your doctor says it is absolutely necessary.
- Do not use while breastfeeding.