Vortioxetine Krka
Vortioxetine Krka is an antidepressant used to treat severe depression in adults.
Form
tabletti, kalvopäällysteinen
Strength
10 mg
Active Ingredient
Vortioxetine hydrobromide
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
For adults under 65, the usual dose is 10 mg once daily, adjusted by your doctor. For those 65 and older, the starting dose is 5 mg once daily.
Method
Take one tablet with a glass of water, with or without food.
Important
The maximum daily dose is 20 mg.
Possible Side Effects
COMMON
- •Nausea
COMMON
- •Diarrhea, constipation, vomiting
- •Dizziness
- •Itching all over the body
- •Unusual dreams
- •Increased sweating
- •Indigestion
RARE
- •Flushing
- •Night sweats
- •Blurred vision
- •Involuntary tremors
- •Hallucinations (seeing, hearing, or feeling things that are not there)
- •Dilated pupils (which may increase the risk of glaucoma)
- •Low blood sodium (symptoms can include dizziness, weakness, confusion, sleepiness, or severe tiredness, or feeling unwell or sick; more serious symptoms are fainting, seizures, or falls)
- •Serotonin syndrome
- •Allergic reactions (which can be severe and cause swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing, and/or a sudden drop in blood pressure that makes you feel dizzy or faint)
- •Hives
- •Excessive or unexplained bleeding (including bruises, nosebleeds, and bleeding from the stomach, intestines, or vagina)
- •Rash
- •Sleep disturbances (insomnia)
- •Agitation and aggression
- •Headache
- •Increased levels of a hormone called prolactin in the blood
- •Restlessness (akathisia)
- •Teeth grinding (bruxism)
- •Inability to open mouth (trismus)
- •Restless legs syndrome (an irresistible urge to move the legs to stop painful or uncomfortable sensations, often occurring at night)
- •Abnormal milk secretion from the breast (galactorrhea)
Important Warnings
- Do not take Vortioxetine Krka if you are allergic to vortioxetine or any other ingredients in this medicine.
- Do not take Vortioxetine Krka if you are taking other antidepressants called non-selective monoamine oxidase inhibitors (MAOIs) or selective MAO-A inhibitors. Ask your doctor if you are unsure.
- Tell your doctor if you are taking other serotonergic medicines (like strong pain relievers or migraine medicines ending in '-triptan'). Taking them together can increase the risk of serotonin syndrome, which can cause hallucinations, involuntary twitching, fast heart rate, and fever.
- Tell your doctor if you have had seizures or if you have epilepsy. Treatment will be stopped if you get seizures or if they get worse.
- Tell your doctor if you have had mania.
Show 11 more warnings
- Tell your doctor if you easily bleed or bruise, or if you are pregnant.
- Tell your doctor if you have low sodium levels in your blood.
- Tell your doctor if you are 65 years old or older.
- Tell your doctor if you have severe kidney disease, liver disease, or liver cirrhosis.
- Tell your doctor if you have or have had high eye pressure or glaucoma. Contact your doctor if you start to feel eye pain and blurred vision during treatment.
- If you are being treated with an antidepressant like vortioxetine and experience feelings of aggression, agitation, anger, or irritability, contact your doctor.
- If you have thoughts of harming yourself or suicide, contact a doctor or go to a hospital immediately.
- Vortioxetine Krka should not be used by children or adolescents under 18 years of age.
- It is not recommended to use this medicine with alcohol.
- Vortioxetine Krka should not be used during pregnancy unless your doctor says it is absolutely necessary.
- Vortioxetine Krka should not be used during breastfeeding.