Voriconazole STADA
Voriconazole Stada is an antifungal medicine that works by killing or stopping the growth of fungi that cause infections.
Form
infuusiokonsentraatti, liuosta varten
Strength
10 mg/ml
Active Ingredient
Voriconazole
Manufacturer
STADA Arzneimittel AG
How to Use
Dosage
Your doctor will determine your dose based on your weight and infection. Typically, adults receive a loading dose of 6 mg per kg every 12 hours for the first day, followed by a maintenance dose of 4 mg per kg twice daily. Doses for children vary by age and weight.
Method
This medicine is given as a slow drip into a vein (intravenous infusion) over 1 to 3 hours, at a maximum rate of 3 mg per kg per hour.
Important
The maximum daily dose for maintenance is typically 8 mg per kg (4 mg/kg given twice daily) for adults. Your doctor will adjust the dose as needed.
Possible Side Effects
COMMON
- •Vision changes, such as blurred vision, altered color vision, or increased sensitivity to light
- •Fever
- •Rash
- •Nausea, vomiting, diarrhea
- •Headache
- •Swelling in arms and legs
- •Abdominal pain
- •Difficulty breathing
- •High liver enzyme levels in blood tests
- •Sinus infection, gum inflammation, chills, weakness
- •Low numbers of red or white blood cells, or platelets (cells that help blood clot)
- •Low blood sugar, low potassium or sodium in blood
- •Anxiety, depression, confusion, agitation, trouble sleeping, hallucinations
- •Seizures, tremors, uncontrolled muscle movements, tingling or unusual skin sensations, increased muscle tone, drowsiness, dizziness
- •Bleeding in the eye
- •Heart rhythm problems (very fast or very slow heart rate), fainting
- •Low blood pressure, vein inflammation (which can cause blood clots)
- •Sudden difficulty breathing, chest pain, swelling of the face (mouth, lips, and around eyes), fluid in the lungs
- •Constipation, indigestion, lip inflammation
- •Yellowing of skin or eyes (jaundice), liver inflammation, liver damage
- •Skin rashes that can be severe, including blistering and peeling, flat red areas with small bumps, or general skin redness
- •Itching
- •Hair loss
- •Back pain
- •Kidney failure, blood in urine, abnormal kidney function test results
- •Reactions at the infusion site
- •Allergic reactions or a stronger immune response
RARE
- •Flu-like symptoms, digestive tract irritation, inflammation of lymph vessels, or diarrhea due to antibiotics
- •Inflammation of the lining inside the abdomen and organs
- •Swollen lymph nodes (sometimes painful), bone marrow not producing enough blood cells, increased eosinophils (a type of white blood cell)
- •Adrenal glands not working well (adrenal insufficiency), or underactive thyroid
- •Abnormal brain activity, symptoms similar to Parkinson's disease, or nerve damage (numbness, pain, tingling, burning in hands/feet)
- •Balance problems, or difficulty with muscle coordination
- •Brain swelling
- •Double vision, severe eye problems (including eye/eyelid pain/inflammation), abnormal eye movements, optic nerve damage (vision loss), or swelling of the optic disc
- •Reduced sense of touch, distorted taste, hearing difficulties, ringing in ears, or vertigo (spinning sensation)
- •Inflammation of internal organs (like the pancreas and small intestine), or swelling and inflammation of the tongue
- •Enlarged liver, liver failure, gallbladder disease, or gallstones
- •Joint inflammation, or inflammation of veins under the skin (with possible blood clot formation)
- •Kidney inflammation, protein in urine, or kidney damage
- •Very fast heart rate or skipped heartbeats with irregular electrical signals
- •Abnormal heart tracing (ECG)
- •High blood cholesterol, or high blood urea
- •Severe allergic skin reactions (including life-threatening skin diseases with painful blisters/sores), hives, severe sun reaction, skin discoloration (red/purple), eczema, or rapid swelling under the skin
- •Small, dry, flaky skin patches, sometimes thickened or with horn-like growths
- •Freckles and dark spots on skin
- •Skin cancer
- •Inflammation of tissue around bone
- •Red, scaly patches or ring-shaped skin lesions that might be a sign of an autoimmune disease (cutaneous lupus erythematosus)
- •Worsening brain function due to severe liver disease
- •Destruction of most optic nerve fibers, cloudy cornea, or involuntary eye movements
- •Blistering rash caused by sun exposure (bullous photosensitivity)
- •Immune system attacking parts of the peripheral nervous system
- •Life-threatening heart rhythm or conduction problems
- •Life-threatening allergic reaction
- •Blood clotting disorder
Important Warnings
- Do not use if you are allergic to voriconazole or any other ingredient in this medicine.
- Stop using Voriconazole Stada and contact your doctor immediately if you experience a rash, yellowing of skin or eyes (jaundice), abnormal liver blood test results, or inflammation of the pancreas (pancreatitis).
- Tell your doctor if you have or have had liver problems or heart problems (like an irregular heartbeat or abnormal ECG). Your doctor will monitor these conditions.
- This medicine can make your skin more sensitive to the sun. Avoid direct sunlight and always use high-factor sunscreen, even for children.
- If you notice severe sunburn, a bad rash, skin blisters, or bone pain, inform your doctor right away.
Show 1 more warnings
- This medicine can affect your vision or make you sensitive to light. If this happens, do not drive or use machines.