Voriconazol Accordpharma
Voriconazol Accordpharma is an antifungal medicine that works by killing or stopping the growth of fungi that cause infections.
Form
infuusiokuiva-aine, liuosta varten
Strength
200 mg
Active Ingredient
Voriconazole
Manufacturer
Accord Healthcare B.V.
How to Use
Dosage
For the first 24 hours (loading dose), 6 mg/kg every 12 hours. After the first 24 hours (maintenance dose), 4 mg/kg twice daily.
Method
Given as an intravenous infusion (drip into a vein) at a maximum rate of 3 mg/kg/hour over 1 to 3 hours.
Important
The maximum daily maintenance dose is typically 8 mg/kg, given as 4 mg/kg twice a day. Your doctor may adjust this.
Possible Side Effects
COMMON
- •Blurred vision, changes in color vision, sensitivity to light, or seeing flashing lights.
- •Fever.
- •Skin rash.
- •Feeling sick (nausea), throwing up (vomiting), or diarrhea.
- •Headache.
- •Swelling in arms and legs.
- •Stomach ache.
- •Difficulty breathing.
- •High levels of liver enzymes in blood tests.
- •Low numbers of red or white blood cells (sometimes with fever), or platelets.
- •Low blood sugar, low potassium, or low sodium in the blood.
- •Anxiety, depression, confusion, agitation, trouble sleeping, or hallucinations.
- •Seizures, tremors, uncontrolled muscle movements, tingling or unusual skin sensations, drowsiness, or dizziness.
- •Irregular heartbeat, including very fast or very slow heart rate, or fainting.
- •Yellow skin or eyes (jaundice), liver inflammation, or liver damage.
- •Kidney failure, blood in urine, or changes in kidney blood tests.
- •Sunburn or severe skin reaction after sun exposure.
- •Hair loss.
RARE
- •Overactive thyroid gland.
- •Severe brain problems due to liver disease.
- •Damage to the optic nerve, cloudy cornea, or involuntary eye movements.
- •Blistering skin reaction to light (photosensitivity).
- •A disorder where the body's immune system attacks peripheral nerves.
- •Life-threatening allergic reaction.
Important Warnings
- Tell your doctor if you've had an allergic reaction to other similar medicines (azoles).
- Inform your doctor if you have or have had liver problems. Your doctor might give you a lower dose and will monitor your liver with blood tests.
- Tell your doctor if you have a known heart muscle disease, irregular heartbeat, slow heartbeat, or abnormal ECG (long QTc syndrome).
- Avoid direct sunlight and protect your skin with clothing and high SPF sunscreen, as this medicine can make your skin more sensitive to the sun.
- Contact your doctor immediately if you get sunburn, severe rash, blisters, or bone pain while taking this medicine.
Show 3 more warnings
- Long-term use of this medicine may slightly increase the risk of skin cancer. Your doctor may recommend regular skin checks.
- Tell your doctor if you notice signs of adrenal insufficiency (e.g., severe tiredness, muscle weakness, weight loss) or Cushing's syndrome (e.g., weight gain, round face, darker skin).
- Your doctor will monitor your kidney function with blood tests.