Vobanzl
Vobanzl is an antifungal medicine that kills fungi or stops their growth in severe fungal infections in adults and children over 2 years old.
Form
infuusiokuiva-aine, liuosta varten
Strength
200 mg
Active Ingredient
Voriconazole
Manufacturer
Alban Pharma GmbH
How to Use
Dosage
Loading dose: 6 mg per kilogram of body weight every 12 hours for the first 24 hours. Maintenance dose: 4 mg per kilogram of body weight twice daily. Your doctor might reduce the dose to 3 mg/kg twice daily based on how well the treatment works.
Method
The medicine is given as a slow drip into a vein (infusion) over 1 to 3 hours.
Important
The maximum daily dose for adults is typically 8 mg per kilogram of body weight during maintenance treatment.
Possible Side Effects
COMMON
- •vision problems (like blurred vision, changes in color vision, sensitivity to light)
- •fever
- •rash
- •nausea, vomiting, diarrhea
- •headache
- •swelling in arms and legs
- •stomach pain
- •difficulty breathing
- •increased liver enzyme levels
RARE
- •low blood cell counts (red, white, or platelets)
- •changes in blood sugar or electrolyte levels (like potassium or sodium)
- •anxiety, confusion, depression, trouble sleeping, or hallucinations
- •seizures, shaking, tingling skin, or dizziness
- •problems with heart rhythm or blood pressure
- •severe skin rashes, blistering, or peeling skin
- •liver inflammation, yellowing of skin (jaundice)
- •kidney problems, changes in kidney tests
Important Warnings
- Do not use if you are allergic to voriconazole or any other ingredients.
- Avoid direct sunlight and use high-SPF sunscreen. Your skin may become more sensitive to UV light, which also applies to children.
- Tell your doctor immediately if you experience sunburn, a severe rash or blisters, or bone pain while taking Vobanzl.
- If you have liver disease, your doctor might give you a lower dose and will monitor your liver function with blood tests.
- Inform your doctor if you have a heart muscle disease, irregular heartbeat, slow heart rate, or an abnormal ECG (a 'long QTc syndrome').
Show 3 more warnings
- Vobanzl should not be given to children under 2 years old.
- Do not use Vobanzl during pregnancy unless your doctor says so. Women who can become pregnant must use reliable birth control.
- Vobanzl can cause blurred vision or sensitivity to light. If you have these symptoms, do not drive or use machinery.