Vesanoid
Vesanoid is used to treat a specific type of leukemia (acute promyelocytic leukemia) by slowing down the growth of certain abnormal blood cells.
Form
kapseli, pehmeä
Strength
10 mg
Active Ingredient
Tretinoin
Manufacturer
Cheplapharm Arzneimittel GmbH
How to Use
Dosage
The typical daily dose for adults is 45 mg per square meter of body surface area (about 8 capsules).
Method
Swallow the capsules whole with water, preferably with or immediately after a meal. Do not chew them.
Important
The maximum daily dose for adults is 45 mg per square meter of body surface area, divided into two equal doses.
Possible Side Effects
COMMON
- •Hair loss
- •Irregular heartbeat
- •Changes in vision and hearing
- •Bone or joint pain, chest pain or stomach ache
- •Rash, itchy skin, redness, peeling skin or inflammation
- •Dry skin, mouth and nose; swollen, dry and chapped lips
- •Breathing difficulties, such as worsening asthma or respiratory failure
- •Conjunctivitis or dry eyes, which may cause discomfort for contact lens users
- •Sleep problems
- •Increased sweating
- •Headache or dizziness
- •Fatigue, feeling cold or general malaise
- •Confusion, anxiety or depression
- •Tingling or numbness in arms or legs
- •Loss of appetite, nausea, vomiting, upset stomach, stomach pain, pancreatitis, lip inflammation, diarrhea or constipation
- •Changes in blood test results, such as elevated liver enzymes (transaminases), creatinine, or blood fats (triglycerides and cholesterol)
RARE
- •Genital ulcers
- •Severe bacterial infections (necrotizing fasciitis)
- •Kidney problems (kidney infarction)
- •Muscle swelling or blood vessel swelling (vasculitis)
- •Red painful lumps under the skin, usually on the shins (erythema nodosum)
- •Loss of appetite, nausea or vomiting, headache, feeling sleepy or weak (possible symptoms of high blood calcium levels)
- •Other changes in blood test results, such as excessive platelet count (thrombocytosis), changes in white blood cell count (basophilia) or increased histamine levels
- •Inflammation of the heart muscle (myocarditis) or the outer sac of the heart (pericarditis), which can cause shortness of breath, palpitations, or chest pain
Important Warnings
- Do not use Vesanoid if you are allergic to tretinoin, other retinoids (like isotretinoin), peanuts, or soy.
- Do not use if you are pregnant, planning to become pregnant, or breastfeeding, as it can harm the baby.
- Avoid taking Vesanoid with Vitamin A supplements, tetracycline antibiotics, or other retinoid medicines.
- Tell your doctor if you have a history of mental health issues like depression or mood swings, as Vesanoid can affect your mood.
- This medicine may affect your ability to drive or operate machinery, especially if you experience dizziness or severe headaches.
Show 7 more warnings
- Seek immediate medical attention if you experience severe headaches with nausea/vomiting, breathing difficulties, fever, dizziness, or chest/back pain.
- Contact your doctor if you have severe stomach pain radiating to your back (possible pancreatitis).
- Report to your doctor if you develop fever with dark, raised skin patches, especially on the face or neck (possible Sweet's syndrome).
- Inform your doctor immediately if you have painful leg swelling, sudden chest pain, or breathing difficulties (possible blood clot).
- Tell your doctor if you experience chest pain radiating to your arm or neck (possible heart attack).
- Consult your doctor if you have double vision and dizziness, especially with nausea/vomiting, ringing in the ears, and headache (possible increased pressure in the skull).
- Report unexplained headache or migraine with vision problems (possible stroke).