Veramacor

Veramacor is used to treat abnormal heart rhythms, such as irregular or excessively fast heartbeats.

Form
injektio-/infuusioneste, liuos
Strength
2.5 mg/ml
Active Ingredient
Verapamil hydrochloride
Manufacturer
Macure Pharma ApS

How to Use

Dosage

For adults, 5 mg is given into a vein slowly over 2 minutes. If more is needed, another 5 mg can be given after 5-10 minutes. It can also be given as a drip into a vein at 5-10 mg per hour. For children 1-15 years, the dose is 0.1-0.3 mg per kg of body weight (usually 2-5 mg) given slowly over at least 2 minutes. A second dose can be given after 30 minutes if the first one didn't work enough.

Method

This medicine is given as an injection into a vein by a doctor or nurse.

Important

The maximum daily dose for adults is 100 mg. For children 1-15 years, a single dose should not be more than 5 mg initially, and not more than 10 mg for a repeated dose.

Possible Side Effects

COMMON
  • Dizziness
  • Headache
  • Slow heart rate
  • Flushing
  • Low blood pressure
  • Constipation
  • Nausea
RARE
  • Abdominal pain
  • Fatigue
  • Skin tingling
  • Tremor
  • Drowsiness
  • Ringing in the ears (tinnitus)
  • Vomiting
  • Increased sweating
  • Movement disorders
  • Paralysis
  • Seizures
  • Elevated potassium levels
  • Nervousness
  • Vertigo
  • Heart attack
  • Abnormal heart rhythm
  • Stomach upset
  • Gum swelling
  • Intestinal obstruction
  • Loss of appetite, fever, weakness
  • Hair loss (alopecia)
  • Itching
  • Joint and/or muscle pain and muscle weakness
  • Kidney problems
  • Impotence
  • Breast enlargement or swelling
  • Milk secretion (related to excess prolactin)

Important Warnings

  • Do not use if you have very low blood pressure due to a severe heart problem (e.g., shock).
  • Do not use if you have heart failure or certain types of heart rhythm disturbances or conduction problems (e.g., second or third-degree heart block, sick sinus syndrome without a pacemaker, very fast heart rate episodes due to Wolff-Parkinson-White syndrome or Lown-Ganong-Levine syndrome).
  • Do not use if you have certain heart valve defects or ventricular tachycardia.
  • Do not use if you are allergic to verapamil or any other ingredient in this medicine.
  • Do not use if you are simultaneously receiving injectable beta-blockers or ivabradine.
Show 7 more warnings
  • Do not use during pregnancy unless your doctor considers it absolutely necessary. Talk to your doctor if you are pregnant or planning to become pregnant.
  • Use during breastfeeding only if your doctor deems it essential for the mother's well-being.
  • Avoid grapefruit juice and alcohol during treatment, as they can alter the effects of the medicine.
  • Do not drive or operate machinery until you know how the medicine affects you, as it may cause dizziness or fatigue.
  • Contact a doctor IMMEDIATELY if you develop yellowing of the skin or eyes, fever, or tenderness in the abdomen (signs of liver dysfunction).
  • Contact a doctor IMMEDIATELY if you develop palpitations, chest pain, swollen ankles, or warm and painful hands/feet (signs of heart failure).
  • Contact a doctor IMMEDIATELY if you develop sudden wheezing, difficulty breathing, swelling of the mouth, lips, or tongue, or a severe rash (signs of a severe allergic reaction).

Use in Elderly Patients

Category D

Avoid use in older adults. Use only in special cases. Reduce the dose in moderately severe renal impairment. May exacerbate heart failure. Significant adverse effects include bradycardia, constipation, heart failure and swelling. Consider the numerous potential interactions. Avoid grapefruit. (updated 17.2.2025)