Venorion

Venorion is an antidepressant medication used to treat depression and anxiety disorders.

Form
depotkapseli, kova
Strength
75 mg
Active Ingredient
Venlafaxine hydrochloride
Manufacturer
Orion Corporation

How to Use

Dosage

The usual starting dose is 75 mg daily for depression and anxiety; for panic disorder, the dose starts at 37.5 mg and is gradually increased.

Method

Take the capsules whole with liquid and food, at approximately the same time each day, either in the morning or evening. Do not open, crush, chew, or dissolve the capsules.

Important

For depression, the maximum dose is 375 mg daily; for anxiety disorders, the maximum dose is 225 mg daily.

Possible Side Effects

COMMON
  • Headache
  • Dizziness
  • Drowsiness
  • Insomnia
  • Nausea
  • Dry mouth
  • Constipation
  • Sweating (including night sweats)
  • Decreased appetite
  • Confusion
  • Feeling unreal or detached from yourself
  • Lack of orgasm
  • Decreased sex drive
  • Agitation
  • Nervousness
  • Abnormal dreams
  • Tremors
  • Feeling restless or unable to sit or stand still
  • Tingling or numbness
  • Changes in taste
  • Increased muscle tension
  • Vision problems (blurry vision, dilated pupils, trouble focusing)
  • Ringing in the ears (tinnitus)
  • Fast heartbeat, palpitations
  • High blood pressure
  • Flushing
  • Shortness of breath
  • Yawning
  • Vomiting
  • Diarrhea
  • Mild rash
  • Itching
  • Increased need to urinate, inability to urinate, difficulty urinating
  • Menstrual problems (increased or irregular bleeding)
  • Ejaculation/orgasm problems (men)
  • Erectile dysfunction (impotence)
  • Weakness (asthenia)
  • Tiredness
  • Chills
  • Weight gain
  • Weight loss
  • Increased cholesterol levels
RARE
  • Swelling of the face, mouth, tongue, throat, hands, or feet, and/or an itchy rash (hives), with difficulty swallowing or breathing (signs of a severe allergic reaction).
  • Chest tightness, wheezing, or difficulty swallowing or breathing.
  • Severe skin rash, itching, or hives (red or pale itchy bumps on the skin), which may lead to severe blistering and peeling of the skin.
  • Serotonin syndrome signs: restlessness, hallucinations, loss of coordination, fast heart rate, increased body temperature, rapid blood pressure changes, diarrhea, coma, nausea, vomiting.
  • Signs of infection: high fever, chills, tremors, headache, sweating, or flu-like symptoms.
  • Unexplained muscle pain, tenderness, or weakness (which can be a sign of rhabdomyolysis).
  • Signs of stress cardiomyopathy: chest pain, shortness of breath, dizziness, fainting, or irregular heartbeat.
  • Coughing, wheezing, and shortness of breath, which may occur with high fever.
  • Black (tarry) stools, blood in stools, or vomiting blood (may indicate internal bleeding).
  • Itching, yellow skin or eyes, dark urine, or flu-like symptoms (may indicate liver inflammation/hepatitis).
  • Heart problems, e.g., changes in heartbeat (fast or irregular) or high blood pressure.
  • Eye problems, e.g., vision disturbances or dilated pupils.
  • Nerve problems, e.g., dizziness, tingling or numbness in the skin, movement disorders (muscle spasms or stiffness), or seizures.
  • Mental health problems, e.g., overactivity or an abnormally intense feeling of well-being.
  • Withdrawal symptoms (upon stopping medication).
  • Prolonged bleeding time (if you get a cut or injury, it may take longer than usual for the bleeding to stop).
  • Overactivity, racing thoughts, and decreased need for sleep (mania).
  • Hallucinations, feeling unreal or detached from reality, problems with orgasm, lack of emotions, excessive excitement, teeth grinding.
  • Fainting, involuntary muscle movements, impaired coordination and balance, dizziness (especially when standing up quickly), decreased blood pressure.
  • Sensitivity to sunlight, bruising, unusual hair loss.
  • Inability to control urine.
  • Muscle stiffness, cramps, and involuntary muscle movements.
  • Slight changes in liver enzyme levels.
  • Confusion and disorientation, often with hallucinations (delirium).
  • Excessive fluid retention (called SIADH syndrome).
  • Low sodium levels in the blood.
  • Severe eye pain and vision loss or blurring.
  • Irregular or very fast heartbeat, which may lead to fainting.
  • Severe stomach or back pain (may indicate a serious problem with your intestines, liver, or pancreas).
  • Prolonged bleeding time, which may indicate low platelet count, increasing the risk of bruising and bleeding.
  • Abnormal breast milk production.
  • Unexpected bleeding, e.g., bleeding gums, blood in urine or vomit, or unexpected bruising or broken capillaries.
  • Suicidal thoughts and behavior.
  • Aggression.
  • Heavy vaginal bleeding shortly after childbirth (postpartum hemorrhage).

Important Warnings

  • Do not take if you are allergic to venlafaxine or any other ingredient in this medicine.
  • Do not take Venorion if you have taken or are taking monoamine oxidase inhibitors (MAOIs) in the last 14 days. Wait at least 7 days after stopping Venorion before starting an MAOI.
  • Tell your doctor if you are taking other medicines that may increase the risk of serotonin syndrome, with symptoms such as restlessness, hallucinations, coordination problems, fast heartbeat, or fever.
  • Talk to your doctor if you have eye problems, such as high pressure in your eyes (glaucoma).
  • Tell your doctor if you have high blood pressure, heart problems, or an abnormal heart rhythm.
Show 12 more warnings
  • Tell your doctor if you have had seizures.
  • Tell your doctor if you have had low sodium levels in your blood (hyponatremia).
  • Tell your doctor if you have a history of bleeding disorders, bruise easily, or have a tendency to bleed.
  • Tell your doctor if you or a close family member has had mania or bipolar disorder.
  • Tell your doctor if you have a history of aggressive behavior.
  • Do not drink alcohol while taking Venorion, as it can cause extreme tiredness and unconsciousness.
  • If you have thoughts of harming yourself or suicide, contact your doctor immediately or go to the nearest hospital. These thoughts may increase at the beginning of treatment.
  • Dry mouth is common and can increase the risk of tooth decay, so good dental hygiene is especially important.
  • Venorion can change your blood sugar levels, so your diabetes medication dose may need to be adjusted.
  • Do not drive or operate machinery until you know how this medicine affects you, as it may impair your ability.
  • If you are pregnant, breastfeeding, or planning a pregnancy, discuss the benefits and risks with your doctor before using this medicine. It may affect the baby.
  • Do not stop taking Venorion or reduce your dose without your doctor's advice, as sudden discontinuation can cause withdrawal symptoms.