Venlafaxin Sandoz

Venlafaxin Sandoz is an antidepressant used to treat depression and anxiety disorders in adults by increasing serotonin and noradrenaline levels in the brain.

Form
depottabletti
Strength
300 mg
Active Ingredient
Venlafaxine hydrochloride
Manufacturer
Sandoz A/S

How to Use

Dosage

The recommended starting dose is 75 mg per day.

Method

Take the tablet whole with liquid, with food, at the same time each day (morning or evening). Do not divide, crush, chew, or dissolve the tablet.

Important

Your doctor may increase the dose up to a maximum of 375 mg per day.

Possible Side Effects

COMMON
  • Dizziness, headache, drowsiness
  • Insomnia
  • Nausea, dry mouth, constipation
  • Sweating (including night sweats)
  • Decreased appetite
  • Confusion, feeling unreal and unfamiliar, lack of orgasm, decreased libido, agitation, nervousness, unusual dreams
  • Tremor, restlessness or inability to sit or stand still, tingling/prickling sensation, changes in taste, increased muscle tension
  • Visual disturbances including blurred vision, dilated pupils, inability of the eye to automatically focus from distant to near objects
  • Ringing in the ears (tinnitus)
  • Rapid heartbeat, palpitations
  • Increased blood pressure, flushing
  • Shortness of breath, yawning
  • Vomiting, diarrhea
  • Mild rash, itching
  • Increased urge to urinate, inability to urinate, difficulty urinating
  • Menstrual disorders such as increased menstrual bleeding or irregular bleeding, ejaculation/orgasm disorders (men), erectile dysfunction (impotence)
  • Weakness, fatigue, chills
  • Weight gain, weight loss
  • Increased cholesterol levels
RARE
  • Swelling of the face, mouth, tongue, throat, hands or feet, and/or itchy rash (hives), difficulty swallowing and breathing.
  • Chest tightness, wheezing, difficulty swallowing or breathing
  • Severe skin rash, itching, or hives (red or pale, often itchy bumps on the skin)
  • Signs and symptoms of serotonin syndrome: restlessness, hallucinations, clumsiness, rapid heartbeat, elevated body temperature, rapid blood pressure changes, overactive reflexes (muscle jerks), diarrhea, coma, nausea, vomiting.
  • Signs of infection, such as high fever, chills, tremors, headache, and flu-like symptoms. These may indicate a blood disorder that increases susceptibility to inflammation.
  • Severe rash that can lead to severe blistering and peeling of the skin
  • Unexplained muscle pain, tenderness, or weakness. This may be a sign of rhabdomyolysis.
  • Hyperactivity, racing thoughts, and decreased need for sleep (mania)
  • Hallucinations, feeling unreal and unfamiliar, orgasm disorders, lack of emotions, excessive enthusiasm, teeth grinding
  • Fainting, involuntary jerky muscle movements, impaired coordination and balance
  • Dizziness (especially when standing up quickly), decreased blood pressure
  • Bloody vomit, black, tarry stools or blood in stools, which may indicate internal bleeding
  • Sensitivity to sunlight, bruising, unusual hair loss
  • Urinary incontinence
  • Muscle stiffness, cramps, and involuntary muscle movements
  • Slight changes in liver enzyme levels in the blood
  • Seizures
  • Coughing, wheezing, and shortness of breath, possibly with high body temperature
  • Confusion and disorientation, often with hallucinations (delirium)
  • Excessive water retention (SIADH syndrome)
  • Decreased sodium levels in the blood
  • Severe eye pain and impaired or blurred vision
  • Heart rate changes to unusually fast or irregular, which can lead to fainting
  • Severe stomach or back pain (which may be due to a serious bowel, liver, or pancreas problem)
  • Itching, yellow skin or whites of the eyes, dark urine, or flu-like symptoms, which may be signs of liver inflammation (hepatitis)
  • Prolonged bleeding time, which may be a sign of low platelet count, increasing the risk of bruising and bleeding
  • Abnormal breast milk production
  • Unexpected bleeding, e.g., bleeding gums, blood in urine or vomit, or unexpected bruising or ruptured superficial blood vessels

Important Warnings

  • Do not use if you are allergic to venlafaxine or any other ingredients in this medicine.
  • Do not use with MAO inhibitors (medicines for depression or Parkinson's disease) or within 14 days of stopping them; wait at least 7 days after stopping Venlafaxin Sandoz before starting an MAO inhibitor.
  • Avoid alcohol during treatment as it can cause extreme tiredness and unconsciousness.
  • If you have suicidal thoughts or feel your depression worsening, contact a doctor or go to a hospital immediately.
  • Dry mouth is common and can increase the risk of tooth decay; maintain good dental hygiene.
Show 6 more warnings
  • If you have diabetes, this medicine may alter blood sugar levels, and your diabetes medication dosage might need adjustment.
  • The medicine can cause sexual dysfunction, which may persist after stopping treatment.
  • This medicine is generally not recommended for children and adolescents under 18 years of age.
  • Do not drive or operate machinery until you know how this medicine affects you.
  • If you are pregnant or breastfeeding, talk to your doctor before using this medicine.
  • This medicine contains lactose; if you have a sugar intolerance, discuss it with your doctor.