Venlafaxin Sandoz

Venlafaxin Sandoz is an antidepressant used to treat depression and anxiety disorders.

Form
depottabletti
Strength
225 mg
Active Ingredient
Venlafaxine hydrochloride
Manufacturer
Sandoz A/S

How to Use

Dosage

The usual starting dose is 75 mg per day for depression, generalized anxiety disorder, and social phobia. For panic disorder, the starting dose is 37.5 mg, which the doctor will gradually increase.

Method

Take the tablets whole with liquid and with food. Do not divide, crush, chew, or dissolve them. Take your dose at approximately the same time each day, either in the morning or in the evening.

Important

For depression, the maximum dose is 375 mg per day. For generalized anxiety disorder, social phobia, and panic disorder, the maximum dose is 225 mg per day.

Possible Side Effects

COMMON
  • Dizziness, headache, drowsiness
  • Insomnia
  • Nausea, dry mouth, constipation
  • Sweating (including night sweats)
  • Decreased appetite
  • Confusion, feeling unreal or foreign, absence of orgasm, decreased libido, agitation, nervousness, unusual dreams
  • Tremor, restlessness or inability to sit or stand still, tingling/pins and needles, taste disturbances, increased muscle tone
  • Visual disturbances including blurred vision, dilated pupils, inability of the eye to automatically change focus from distant to near objects
  • Ringing in the ears (tinnitus)
  • Rapid heartbeat, palpitations
  • Increased blood pressure, flushing
  • Shortness of breath, yawning
  • Vomiting, diarrhea
  • Mild rash, itching
  • Increased need to urinate, inability to urinate, difficulty urinating
  • Menstrual disorders (increased bleeding or irregular bleeding), ejaculation/orgasm disorders (men), erectile dysfunction (impotence)
  • Weakness, fatigue, chills
  • Weight gain, weight loss
  • Increased cholesterol levels
RARE
  • Swelling of the face, mouth, tongue, throat, hands or feet, and/or itchy welts (hives), difficulty swallowing or breathing.
  • Coughing, wheezing, shortness of breath, possibly with high body temperature.
  • Severe rash that can lead to severe blistering and skin peeling.
  • Serotonin syndrome symptoms like restlessness, hallucinations, clumsiness, rapid heartbeat, increased body temperature, rapid blood pressure changes, overactive reflexes, diarrhea, coma, nausea, vomiting. In severe cases, it can resemble neuroleptic malignant syndrome with fever, palpitations, sweating, severe muscle rigidity, confusion, or increased muscle enzyme levels.
  • Signs of infection (high fever, chills, tremor, headache, flu-like symptoms) due to a blood disorder.
  • Unexplained muscle pain, tenderness, or weakness. This can be a sign of rhabdomyolysis.
  • Symptoms of stress cardiomyopathy: chest pain, shortness of breath, dizziness, fainting, irregular heartbeat.
  • Hyperactivity, racing thoughts, decreased need for sleep (mania).
  • Hallucinations, feeling unreal or foreign, orgasm disorders, lack of emotion, over-excitement, teeth grinding.
  • Fainting, involuntary muscle twitching, impaired coordination and balance.
  • Dizziness (especially when standing up quickly), decreased blood pressure.
  • Vomiting blood, black/tarry stools or blood in stools, which may indicate internal bleeding.
  • Sensitivity to sunlight, bruising, unusual hair loss.
  • Inability to control urination.
  • Muscle stiffness, cramps, involuntary muscle movements.
  • Slight changes in liver enzyme levels in blood.
  • Seizures.
  • Confusion and disorientation, often with hallucinations (delirium).
  • Excessive water retention (SIADH).
  • Decreased blood sodium levels.
  • Severe eye pain and vision impairment or blurring.
  • Abnormally fast or irregular heartbeat, which can lead to fainting.
  • Severe abdominal or back pain (which may indicate a serious intestinal, liver, or pancreatic problem).
  • Itching, yellow skin or whites of eyes, dark urine or flu-like symptoms, which may be signs of liver inflammation (hepatitis).
  • Prolonged bleeding time, which may indicate low platelet count, increasing the risk of bruising and bleeding.
  • Abnormal milk secretion from breasts.
  • Unexpected bleeding, e.g., bleeding gums, blood in urine or vomit, or unexpected bruises or ruptured superficial blood vessels.
  • Suicidal thoughts and behavior.
  • Aggression.
  • Very heavy vaginal bleeding shortly after childbirth (postpartum hemorrhage).

Important Warnings

  • If you are allergic to venlafaxine or any other ingredient in this medicine.
  • If you are taking or have taken certain medicines for depression or Parkinson's disease (MAOIs) in the last 14 days.
  • If you are taking other medicines that may increase the risk of serotonin syndrome.
  • If you have difficulty swallowing or stomach/intestinal problems that slow food movement.
  • If you have eye problems, such as certain types of glaucoma (increased eye pressure).
Show 12 more warnings
  • If you have had high blood pressure, heart problems, or an abnormal heart rhythm.
  • If you have a history of seizures.
  • If your blood sodium levels have been low (hyponatremia).
  • If you have a history of bleeding disorders or take blood thinners like warfarin.
  • If you or a close family member has had mania or bipolar disorder.
  • If you have a history of aggressive behavior.
  • If you feel restless or are unable to sit or stand still during the initial weeks of treatment, tell your doctor.
  • Do not drink alcohol during Venlafaxin Sandoz treatment, as it can cause extreme tiredness and unconsciousness and worsen symptoms.
  • If you have thoughts of harming yourself or suicide, contact your doctor or go to the nearest hospital immediately.
  • This medicine can cause dry mouth, which increases the risk of tooth decay, so good dental hygiene is important.
  • Do not drive or use machines until you know how this medicine affects you, as it may impair your ability.
  • This medicine contains lactose. If you have a sugar intolerance, consult your doctor before taking it.