Venlafaxin ratiopharm
Venlafaxine ratiopharm is an antidepressant used to treat depression, generalized anxiety disorder, social anxiety, and panic disorder.
Form
depotkapseli, kova
Strength
75 mg
Active Ingredient
Venlafaxine hydrochloride
Manufacturer
Teva B.V.
How to Use
Dosage
The typical starting dose is 75 mg once daily, but your doctor may adjust it.
Method
Take the capsule by mouth with food, swallowed whole with liquid, at about the same time each day (morning or evening). Do not break, crush, chew, or dissolve the capsules.
Important
The maximum daily dose is up to 375 mg, as prescribed by your doctor.
Possible Side Effects
COMMON
- •Dizziness, headache, drowsiness
- •Insomnia (difficulty sleeping)
- •Nausea, dry mouth, constipation
- •Sweating (including night sweats)
- •Decreased appetite
- •Confusion, feeling detached from reality, lack of orgasm, decreased sexual desire, agitation, nervousness, abnormal dreams
- •Tremor, restlessness or inability to sit or stand still, tingling or prickling sensations, changes in taste, increased muscle tone
- •Vision problems (blurred vision, dilated pupils, difficulty focusing), ringing in ears (tinnitus)
- •Rapid heart rate, palpitations, increased blood pressure, flushing
- •Shortness of breath, yawning
- •Vomiting, diarrhea
- •Mild rash, itching
- •Frequent urination, inability to urinate, difficulty urinating
- •Irregular periods (increased or abnormal bleeding), abnormal ejaculation or orgasm (men), erectile dysfunction
- •Weakness, fatigue, chills
- •Weight gain, weight loss
- •Increased cholesterol levels
RARE
- •Hyperactivity, racing thoughts, decreased need for sleep (mania)
- •Hallucinations, feeling detached from reality, abnormal orgasm, lack of emotion, hyperexcitability, teeth grinding
- •Fainting, involuntary muscle movements, impaired coordination and balance
- •Dizziness (especially when standing up too quickly), decreased blood pressure
- •Vomiting blood, black tarry stools or blood in stools (signs of internal bleeding)
- •Sensitivity to sunlight, bruising, abnormal hair loss, urinary incontinence
- •Muscle stiffness, cramps, involuntary muscle movements
- •Slight changes in blood liver enzyme levels
- •Seizures
- •Coughing, wheezing, shortness of breath, possibly with fever
- •Excessive water retention (SIADH)
- •Decreased blood sodium levels
- •Severe eye pain and vision loss or blurring
- •Severe stomach or back pain (may indicate a serious intestinal, liver, or pancreatic problem)
- •Itching, yellow skin or eyes, dark urine or flu-like symptoms (may indicate liver inflammation (hepatitis))
- •Confusion and disorientation, often with hallucinations (delirium)
- •Unusually fast or irregular heartbeat, which may lead to fainting
- •Prolonged bleeding time (may indicate low platelet count, increasing risk of bruising and bleeding)
- •Abnormal breast milk production
- •Unexpected bleeding (e.g., bleeding gums, blood in urine or vomit, or unexpected bruising or ruptured superficial blood vessels)
- •Suicidal thoughts and behavior (if occurring, seek immediate help)
- •Aggression
- •Dizziness
- •Heavy vaginal bleeding shortly after childbirth
Important Warnings
- Do not take if you are allergic to venlafaxine or any other ingredient in this medicine.
- Do not take if you are currently taking or have taken MAO inhibitors (another type of antidepressant) in the last 14 days.
- Talk to your doctor if you use other medicines that may increase the risk of Serotonin Syndrome (a serious condition with symptoms like restlessness, hallucinations, fast heartbeat, fever, confusion, and muscle stiffness).
- Seek immediate medical help if you experience signs of a severe allergic reaction, such as swelling of your face, mouth, tongue, throat, hands, or feet, or difficulty swallowing or breathing.
- If you have eye problems (like glaucoma), high blood pressure, heart problems, or an abnormal heart rhythm.
Show 12 more warnings
- If you have a history of seizures, low sodium levels in your blood, or a tendency to bruise or bleed easily.
- If you or a close relative has had mania or bipolar disorder, or if you have a history of aggressive behavior.
- Do not drink alcohol while taking this medicine.
- If you have thoughts of harming yourself or suicide, especially if you are a young adult (under 25), contact your doctor or go to the nearest hospital immediately.
- Be aware of symptoms like high fever, chills, tremors, headache, and flu-like symptoms, which could indicate a blood disorder (seek medical help).
- Watch for severe rashes leading to blistering and peeling skin (seek medical help).
- Unexplained muscle pain, tenderness, or weakness could be a sign of a serious condition called rhabdomyolysis (seek medical help).
- Watch for chest pain, shortness of breath, dizziness, fainting, or irregular heartbeat, which could be signs of stress cardiomyopathy (seek medical help).
- Yellow skin or eyes, dark urine, or flu-like symptoms may indicate liver inflammation (hepatitis) (seek medical help).
- Severe stomach or back pain may indicate a serious problem with your intestines, liver, or pancreas (seek medical help).
- If you are pregnant, planning to become pregnant, or breastfeeding, discuss with your doctor before taking this medicine.
- Do not stop taking this medicine or change your dose without first talking to your doctor, even if you feel better.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Serotonergic. A significant adverse effect is low serum sodium level. Increases risk of falls. Consider the numerous potential interactions, especially with drugs that increase the risk of bleeding. Reduce the dose already in mild renal impairment. (updated 12.2.2024)