Venlafaxin ratiopharm
Venlafaxin ratiopharm is a medicine used to treat depression and anxiety disorders.
Form
depotkapseli, kova
Strength
37.5 mg
Active Ingredient
Venlafaxine hydrochloride
Manufacturer
Teva B.V.
How to Use
Dosage
For depression and anxiety, the usual starting dose is 75 mg per day. For panic disorder, treatment often starts with 37.5 mg.
Method
Take the capsules by mouth, whole with liquid, in the morning or evening with food. Do not split, crush, chew, or dissolve them.
Important
For depression, the maximum dose is 375 mg per day. For other anxiety disorders, the maximum is 225 mg per day.
Possible Side Effects
COMMON
- •Dizziness, headache, drowsiness.
- •Insomnia.
- •Nausea, dry mouth, constipation.
- •Sweating (including night sweats).
- •Decreased appetite.
- •Confusion, feeling detached, lack of orgasm, decreased sex drive, agitation, nervousness, unusual dreams.
- •Tremor, restlessness or inability to sit still, tingling, numbness, altered taste, increased muscle tension.
- •Blurred vision, dilated pupils, difficulty focusing eyes.
- •Ringing in the ears (tinnitus).
- •Fast heartbeat, palpitations.
- •Increased blood pressure, flushing.
- •Shortness of breath, yawning.
- •Vomiting, diarrhea.
- •Mild rash, itching.
- •Frequent urge to urinate, inability to urinate, difficulty urinating.
- •Irregular periods (heavy or more frequent), abnormal ejaculation/orgasm (men), erectile dysfunction.
- •Weakness, fatigue, chills.
- •Weight gain or loss.
- •Increased cholesterol levels.
RARE
- •Swelling of the face, mouth, tongue, throat, hands, or feet, itchy rash, or trouble swallowing or breathing.
- •Hyperactivity, racing thoughts, and less need for sleep (mania).
- •Hallucinations, feeling unreal, abnormal orgasm, emotional numbness, overexcitement, teeth grinding.
- •Fainting, involuntary muscle movements, poor coordination and balance.
- •Dizziness (especially when standing up quickly), low blood pressure.
- •Vomiting blood, black tarry stools or blood in stools (signs of internal bleeding).
- •Sensitivity to sunlight, bruising, rash, abnormal hair loss.
- •Urinary incontinence.
- •Muscle stiffness, cramps, and involuntary muscle movements.
- •Slight changes in liver enzyme levels.
- •Seizures.
- •Cough, wheezing, shortness of breath, possibly with fever.
- •Excess water buildup in the body (SIADH syndrome).
- •Low sodium levels in the blood.
- •Severe eye pain and blurred or reduced vision.
- •Severe stomach or back pain (may be a serious problem with your gut, liver, or pancreas).
- •Itching, yellow skin or eyes, dark urine or flu-like symptoms (signs of liver inflammation).
- •Confusion and disorientation, often with hallucinations (delirium).
- •Unusually fast or irregular heartbeat, which may cause fainting.
- •Longer bleeding time if you get a cut or injury, possibly due to low platelets.
- •Unusual milk production from the breasts.
- •Unexpected bleeding, such as bleeding gums, blood in urine or vomit, or unusual bruises or broken blood vessels.
- •Suicidal thoughts and behavior.
- •Aggression.
- •Symptoms of serotonin syndrome such as restlessness, seeing or hearing things that are not there, loss of coordination, fast heartbeat, high body temperature, rapid blood pressure changes, overactive reflexes, diarrhea, coma, nausea, and vomiting.
- •Signs of infection like high fever, chills, shaking, headache, and flu-like symptoms, which may mean a blood problem.
- •Severe rash with blisters and peeling skin.
- •Unexplained muscle pain, tenderness, or weakness (could be rhabdomyolysis).
- •Chest pain, shortness of breath, dizziness, fainting, and irregular heartbeat (stress cardiomyopathy).
Important Warnings
- Do not take if you are allergic to venlafaxine or any other ingredients in this medicine.
- Do not take if you are taking or have taken certain depression medications (MAOIs) in the last 14 days.
- Tell your doctor if you take other medicines that could increase the risk of a serious condition called serotonin syndrome.
- Tell your doctor if you have eye problems, such as glaucoma (high pressure in the eye).
- Tell your doctor if you have high blood pressure.
Show 10 more warnings
- Tell your doctor if you have heart problems or an abnormal heartbeat.
- Tell your doctor if you have had seizures.
- Tell your doctor if you have low sodium levels in your blood.
- Tell your doctor if you bruise easily, have bleeding problems, take blood thinners, or are pregnant.
- Tell your doctor if you or a family member has had mania or bipolar disorder.
- Tell your doctor if you have a history of aggressive behavior.
- Do not drink alcohol during treatment, as it can cause extreme tiredness and unconsciousness.
- If you have thoughts of harming yourself or suicide, contact your doctor immediately or go to the nearest hospital.
- Do not drive or use machinery until you know how this medicine affects you.
- Do not use this medicine during pregnancy or breastfeeding without talking to your doctor about the risks and benefits.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Serotonergic. A significant adverse effect is low serum sodium level. Increases risk of falls. Consider the numerous potential interactions, especially with drugs that increase the risk of bleeding. Reduce the dose already in mild renal impairment. (updated 12.2.2024)