Tubilysin
Tubilysin is an antibiotic used to treat tuberculosis, usually with other tuberculosis medicines.
Form
tabletti
Strength
300 mg
Active Ingredient
Isoniazid
Manufacturer
Orion Corporation
How to Use
Dosage
For adults, the usual recommended dose is 300 mg once a day. For children (over 3 months), the recommended dose is 10 mg/kg daily, up to a maximum of 300 mg daily. Your doctor may prescribe different dosages.
Method
Take the tablets on an empty stomach, 1–2 hours before a meal or 2 hours after a meal, with a glass of water. Take the medicine regularly and do not stop treatment suddenly.
Important
For adults, maximum 300 mg per day or 900 mg three times a week. For children, maximum 300 mg per day.
Possible Side Effects
COMMON
- •Allergic reactions (like fever and skin rashes).
- •Liver damage, sometimes causing yellow skin or eyes (especially in people over 50).
- •Feeling sick (nausea) or throwing up (vomiting).
- •Nerve inflammation, causing tingling or numbness in hands and feet, or sometimes weak and stiff muscles.
- •Skin rashes, itchy bumps on the skin (hives).
- •Tuberculosis symptoms coming back or getting worse, such as cough, fever, tiredness, shortness of breath, headache, not wanting to eat, or weight loss.
RARE
- •Trouble remembering things.
- •Inflammation of the liver.
- •Changes in your blood, like having too few red or white blood cells or platelets.
- •High blood sugar levels.
- •Mood changes, mental illness (psychosis), seizures.
- •Problems with the brain.
- •Inflammation of the nerve that helps you see.
- •Dry mouth.
- •Yellow skin (jaundice), death of liver cells, or liver not working well.
- •Joint problems, breakdown of muscle tissue.
- •Very serious skin reactions (like DRESS, TEN syndromes).
- •A specific type of anemia called sideroblastic anemia.
- •A reaction similar to lupus, with flu-like symptoms (fever, tiredness, headache, muscle/joint pain, rashes) and swollen lymph glands.
- •Too much acid in the body (metabolic acidosis), or not enough niacin (a vitamin).
- •Feeling confused, seeing or hearing things that aren't there, trouble knowing where you are or what time it is.
- •Headache, shaking, dizziness, quick reflexes, or trouble with coordination.
- •Damage to the nerve that helps you see.
- •Inflammation of blood vessels.
- •Allergic inflammation in the lungs.
- •Pancreas inflammation, not wanting to eat, gas, stomach pain, or constipation.
- •Severe red rash with blisters (erythema multiforme), allergic reactions with skin rashes, itching, or hair loss.
- •Red, scaly, widespread rash with bumps under the skin and blisters, often with fever. Usually appears early in treatment.
- •Rheumatic symptoms, joint inflammation.
- •Symptoms similar to lupus, like swollen joints, tiredness, and skin rashes.
- •Difficulty emptying your bladder, kidney damage, including kidney inflammation.
- •Enlargement of breast tissue in men.
Important Warnings
- Do not take if you are allergic to isoniazid, similar substances, or any other ingredient in this medicine.
- Do not take if you have nerve inflammation, acute liver disease, or if you have had severe liver damage or a severe rash after taking isoniazid before.
- Talk to your doctor if you have kidney or liver problems, diabetes, cancer, HIV infection, epilepsy, porphyria, are pregnant or breastfeeding, are elderly, or drink a lot of alcohol.
- Stop taking this medicine and contact your doctor immediately if you develop a severe skin reaction (such as rash, blisters, peeling skin, fever).
- Contact your doctor if you have unexplained loss of appetite, persistent fatigue, jaundice, itching, numbness in hands/feet, abdominal pain, nausea, vomiting, or dark urine.
Show 3 more warnings
- If tuberculosis symptoms return or worsen during treatment, contact your doctor immediately.
- Avoid foods containing tyramine or histamine (such as cheeses, red wine, tuna) and alcohol, as they can increase the risk of side effects.
- Tell your doctor about all other medicines you are taking, as Tubilysin can affect their effectiveness.