Truxal
Truxal helps treat mental health conditions like anxiety, restlessness, and sleep problems, especially with psychoses or severe depression, and can also boost the effects of pain medicines.
Form
tabletti, kalvopäällysteinen
Strength
50 mg
Active Ingredient
Chlorprothixene hydrochloride
Manufacturer
H. Lundbeck A/S
How to Use
Dosage
The dose is set individually by your doctor and depends on your condition.
Method
Swallow the tablets whole with water; do not chew them.
Important
Always follow your doctor's instructions for the maximum daily dose.
Possible Side Effects
COMMON
- •Drowsiness, dizziness, especially at the start of treatment, and low blood pressure when standing up (more common in elderly).
- •Dry mouth, increased saliva, fast heartbeat (palpitations).
- •Pounding, strong, or irregular heartbeats (palpitations).
- •Long-lasting muscle contractions causing twisting or repeated movements or abnormal postures (dystonia), headache.
- •Difficulty focusing eyesight (accommodation disorder), abnormal vision.
- •Constipation, indigestion or upper stomach pain (dyspepsia), nausea.
- •Increased sweating (hyperhidrosis).
- •Muscle pain (myalgia).
- •Tiredness, weakness (asthenia).
- •Insomnia (difficulty sleeping), nervousness, agitation, decreased sex drive (reduced libido).
- •Increased appetite and weight gain.
- •Movement disorders (extrapyramidal symptoms).
RARE
- •Involuntary, repetitive movements of the mouth and tongue (tardive dyskinesia).
- •Parkinsonism, seizures, inability to sit still or restlessness (akathisia).
- •Circular eye movements (oculogyration).
- •Vomiting, diarrhea.
- •Urination problems or inability to urinate (urinary retention).
- •Rash, itching, skin reaction due to light sensitivity, eczema, or skin inflammation.
- •Muscle stiffness.
- •Poor appetite, weight loss.
- •Low blood pressure (hypotension), hot flashes.
- •Abnormal liver function test results.
- •Sexual disorders (delayed ejaculation, erectile dysfunction).
- •Low blood platelet count (thrombocytopenia), low neutrophil white blood cell count (neutropenia), low white blood cell count (leukopenia), severe lack of granulocytes (agranulocytosis).
- •Shortness of breath or painful breathing (dyspnea).
- •High prolactin levels in blood (hyperprolactinemia).
- •High blood sugar levels (hyperglycemia), impaired glucose tolerance.
- •Hypersensitivity, acute whole-body allergic reaction (anaphylaxis).
- •Breast enlargement in men (gynecomastia), excessive milk production (galactorrhea), absent menstrual periods (amenorrhea).
- •Prolonged QT interval (slow heart rate and ECG changes).
- •Heart rhythm disorders (ventricular arrhythmias, ventricular fibrillation, ventricular tachycardia).
- •Torsades de pointes (a specific type of heart rhythm disorder).
- •High fever, unusual muscle stiffness, and confusion, especially with sweating and fast heartbeat (may be signs of neuroleptic malignant syndrome).
- •Yellow skin and whites of the eyes (jaundice), which may indicate liver problems.
- •Prolonged, painful erection.
- •Blood clots, especially in leg veins (swelling, pain, redness), which can travel to the lungs, causing chest pain and breathing difficulties.
Important Warnings
- Do not use Truxal if you are allergic to chlorprothixene or any other ingredient in this medicine.
- Do not use if your consciousness is reduced.
- Do not use if you have or have had heart or blood vessel disease.
- Do not use if you have irregular heartbeat.
- Do not use if you have low potassium or magnesium levels in your blood, or a family history of these.
Show 25 more warnings
- Do not use if you are taking medicines that affect your heart rate.
- Do not use if you have an adrenal gland disease (pheochromocytoma).
- Do not use if you have abnormal blood cell counts.
- Tell your doctor if you have liver or kidney disease.
- Tell your doctor if you have had seizures or convulsions before.
- Tell your doctor if you have an enlarged prostate (for men).
- Tell your doctor if you have myasthenia gravis (a rare condition causing severe muscle weakness).
- Tell your doctor if you have diabetes, as your medication may need adjustment.
- Tell your doctor if you have an organic brain syndrome (caused by alcohol or other substances).
- Tell your doctor if you have risk factors for stroke (e.g., smoking, high blood pressure).
- Tell your doctor if you have or have had prolonged QT interval (slow heart rate and ECG changes).
- Tell your doctor if you are using other antipsychotic medicines.
- Tell your doctor if you have narrow-angle glaucoma or shallow anterior chamber (a rare eye condition), as it can lead to acute glaucoma attacks.
- If you are elderly, be aware of a higher risk of low blood pressure when standing up.
- Tell your doctor if you or anyone in your family has had blood clots.
- Tell your doctor if you have a prolactin-dependent tumor.
- Tell your doctor if you have Parkinson's disease.
- Tell your doctor if you have a disease of blood-forming organs (like bone marrow, spleen, or lymph nodes).
- Tell your doctor if you have an overactive thyroid (hyperthyroidism).
- Tell your doctor if you have urination problems, difficulty urinating, or bowel obstruction.
- Avoid alcohol during treatment, as Truxal can increase its sedative effects and cause drowsiness.
- Do not use Truxal during pregnancy or breastfeeding unless your doctor says it's clearly necessary, as it can affect the baby.
- Truxal can cause drowsiness and dizziness, especially at the start of treatment; do not drive or use machines until these effects pass.
- If you have a sugar intolerance, talk to your doctor before taking this medicine.
- Elderly patients with dementia taking antipsychotics have a slightly higher risk of death compared to those not taking them.
Use in Elderly Patients
Category D
Avoid use in older adults. Anticholinergic. Sedative. Increases the risk of cardiovascular events, QT prolongation and orthostatic hypotension. Increases risk of falls, extrapyramidal symptoms and cognitive impairment. Reduces the effectiveness of drugs for Alzheimer’s disease. (updated 15.1.2024)