Triptyl
Triptyl is a medicine that belongs to a group called tricyclic antidepressants and is used to treat depression, nerve pain, chronic tension headaches, migraines, and bedwetting in children.
Form
tabletti, kalvopäällysteinen
Strength
50 mg
Active Ingredient
Amitriptyline hydrochloride
Manufacturer
Orion Corporation
How to Use
Dosage
For adults, a typical starting dose is 25 mg twice daily, adjusted by your doctor.
Method
Swallow the tablets whole with water. Do not chew them.
Important
The maximum daily dose for adults can be up to 150 mg, as directed by your doctor, depending on the condition being treated.
Possible Side Effects
COMMON
- •Sleepiness/drowsiness
- •Shaking of hands or other body parts
- •Dizziness
- •Headache
- •Irregular, strong or fast heartbeat
- •Dizziness due to low blood pressure when standing up
- •Dry mouth
- •Constipation
- •Nausea
- •Excessive sweating
- •Weight gain
- •Slurred or slow speech
- •Aggression
- •Stuffy nose
- •Confusion
- •Changes in sexual desire or function
- •Difficulty concentrating
- •Changes in taste
- •Numbness or tingling in arms and legs
- •Coordination difficulties
- •Dilated pupils
- •Heart block
- •Fatigue
- •Low sodium levels in the blood
- •Agitation or restlessness
- •Problems with urination
- •Feeling thirsty
RARE
- •Excitement, anxiety, difficulty sleeping, nightmares
- •Seizures
- •Ringing in the ears (tinnitus)
- •High blood pressure
- •Diarrhea, vomiting
- •Skin rash, hives (urticaria), swelling of the face and tongue
- •Increased breast milk production or secretion (without breastfeeding)
- •Increased pressure in the eye
- •Fainting or collapse
- •Worsening heart failure
- •Impaired liver function (e.g., cholestatic liver disease)
- •Reduced appetite
- •Delirium (confusion, loss of reality), hallucinations
- •Abnormal heart rhythm or heartbeat
- •Swollen salivary glands
- •Hair loss
- •Increased sensitivity to sunlight
- •Breast enlargement in men
- •Fever
- •Weight loss
- •Abnormal liver function test results
- •Heart muscle disease
- •Feeling of inner restlessness and strong urge to move constantly
- •Peripheral nerve disorder (e.g., numbness, tingling in legs/feet, impaired sensation)
- •Acute increase in eye pressure
- •Specific abnormal heart rhythms (Torsades de pointes)
- •Allergic inflammation in lung alveoli and lung tissue
- •Increased or decreased blood sugar levels
- •Paranoia (delusions)
- •Movement disorders (involuntary or reduced movements)
- •Heart muscle inflammation due to hypersensitivity
- •Liver inflammation
- •Hot flashes
- •Dry eyes
Important Warnings
- Do not take Triptyl if you are allergic to amitriptyline or any other ingredient in this medicine.
- Do not take Triptyl if you have recently had a heart attack.
- Do not take Triptyl if you have heart problems such as irregular heartbeats (arrhythmias), AV-block, or coronary artery disease.
- Do not take Triptyl if you are taking or have recently taken (within 14 days) MAOI medicines.
- Do not take Triptyl if you have severe liver disease.
Show 8 more warnings
- This medicine should not be used for children under 6 years of age.
- Triptyl can affect your heart rhythm. Tell your doctor if you have a slow heart rate, heart failure, or imbalances in potassium or magnesium, or if you are taking other medicines that can affect your heart.
- If you have thoughts of harming yourself or suicide, contact your doctor or go to a hospital immediately, especially early in treatment.
- Stop taking Triptyl and seek immediate medical help if you develop widespread rash, fever, and swollen lymph nodes (DRESS syndrome), as these can be signs of a severe skin reaction.
- Seek immediate medical attention if you experience blurred vision, rainbow vision, and eye pain, as this could be a sign of acute glaucoma.
- Seek immediate medical attention if you experience severe constipation, abdominal swelling, fever, and vomiting, as these can be signs of paralytic ileus (bowel paralysis).
- Seek immediate medical attention if your skin or the whites of your eyes turn yellow (jaundice), as this could indicate liver problems.
- Seek immediate medical attention if you experience bruising, bleeding, paleness, persistent sore throat, or fever, as these can be signs of blood disorders.
Use in Elderly Patients
Category D
Avoid use in older adults. Anticholinergic. Sedative. Serotonergic. Risk of QT prolongation. Significant adverse effects include confusion, cognitive impairment, arrhythmias and orthostatic hypotension. Increases risk of falls. Consider the numerous potential interactions. Reduces the effectiveness of drugs for Alzheimer’s disease. (updated 12.2.2024)