Triptyl
Triptyl is a medicine used to treat depression, nerve pain, chronic tension headaches, migraines, and bedwetting in children.
How to Use
Dosage
Your doctor will tell you the exact dose. For depression, adults usually start with 25 mg twice daily. For nerve pain, headaches, or migraines, adults often start with 10-25 mg in the evening. For bedwetting, children aged 6-10 take 10-20 mg daily, and children 11 and older take 25-50 mg daily.
Method
Take this medicine exactly as your doctor has told you. Swallow the tablets with a little water. Do not chew them. You can take the medicine with or without food.
The maximum daily dose varies by condition and age. Your doctor will set the highest safe dose for you, which can be up to 150 mg for adult depression, and up to 50 mg for bedwetting in children.
Possible Side Effects
- •Drowsiness or sleepiness
- •Shaking in your hands or other body parts
- •Dizziness
- •Headache
- •Uneven, strong, or fast heartbeat
- •Dizziness when standing up due to low blood pressure
- •Dry mouth
- •Constipation
- •Nausea
- •Excessive sweating
- •Weight gain
- •Slurred or slow speech
- •Aggression
- •Stuffy nose
- •Confusion
- •Sexual changes, such as reduced sex drive or erection problems
- •Problems with attention
- •Changes in taste
- •Numbness or tingling in your hands or feet
- •Problems with coordination
- •Dilated pupils
- •Heart block (a type of irregular heartbeat)
- •Fatigue
- •Low sodium levels in the blood
- •Agitation or physical restlessness
- •Urination problems
- •Feeling thirsty
- •Excitement, anxiety, difficulty sleeping, or nightmares
- •Seizures
- •Ringing in the ears (tinnitus)
- •High blood pressure
- •Diarrhea or vomiting
- •Rash, hives (itchy red bumps), or swelling of the face and tongue
- •Difficulty urinating
- •Increased breast milk production or discharge not related to breastfeeding
- •Increased pressure in the eye
- •Collapse states (sudden loss of strength)
- •Worsening heart failure
- •Worsened liver function (e.g., cholestatic liver disease)
- •Decreased appetite
- •Delirium (a state of severe confusion), confusion, or hallucinations, especially in older patients
- •Abnormal heart rhythm or irregular heartbeat
- •Swollen salivary glands
- •Hair loss
- •Increased sensitivity to sunlight
- •Breast enlargement in men
- •Fever
- •Weight loss
- •Abnormal liver test results
- •Heart muscle disease
- •Feeling restless and a strong need to constantly move
- •Peripheral nerve disorder (e.g., numbness, tingling in limbs, altered sensation)
- •Acute increase in eye pressure
- •Special types of abnormal heart rhythm (called torsades de pointes)
- •Allergic inflammation in the lung air sacs and lung tissue
- •Loss of appetite
- •Increased or decreased blood sugar levels
- •Paranoia (delusions)
- •Movement disorders (involuntary or reduced movements)
- •Heart muscle inflammation due to an allergic reaction
- •Liver inflammation
- •Hot flush
- •Dry eyes
Important Warnings
- Do not take Triptyl if you are allergic to amitriptyline, have recently had a heart attack, have severe heart problems, or severe liver disease.
- Do not take this medicine if you have taken certain other antidepressants (MAOIs) in the last 14 days or moclobemide yesterday.
- Children under 6 years of age should not take this medicine.
- Triptyl can affect your heart rhythm; tell your doctor if you have a slow heart rate or other heart problems.
- If you feel depressed and think about harming yourself, talk to your doctor or go to a hospital right away.
Show 3 more warnings
- Stop taking Triptyl and get medical help immediately if you get a widespread skin rash, fever, or swollen lymph nodes.
- Do not drink alcohol while taking this medicine as it can make you more drowsy.
- Do not drive or use machines if you feel sleepy or dizzy, especially when you first start treatment.
Use in Elderly Patients
Avoid use in older adults. Anticholinergic. Sedative. Serotonergic. Risk of QT prolongation. Significant adverse effects include confusion, cognitive impairment, arrhythmias and orthostatic hypotension. Increases risk of falls. Consider the numerous potential interactions. Reduces the effectiveness of drugs for Alzheimer’s disease. (updated 12.2.2024)