Treosulfan Tillomed
Treosulfan Tillomed is a cancer medicine containing treosulfan, which helps stop cancer growth and is used to treat advanced ovarian cancer after other treatments have been tried.
Form
infuusiokuiva-aine, liuosta varten
Strength
5 g
Active Ingredient
Treosulfan
Manufacturer
Tillomed Pharma GmbH
How to Use
Dosage
Your doctor will calculate your dose based on your blood tests and body size; the dose may be reduced if you are receiving other cancer treatments.
Method
This medicine is given as a drip into a vein (intravenous infusion) by a doctor or nurse, which takes 15-30 minutes.
Important
The medicine is typically given every 3-4 weeks, and there is no specific maximum daily dose.
Possible Side Effects
COMMON
- •Decrease in white blood cells (increased infection risk), platelets (bruising and bleeding), and red blood cells (paleness, weakness, shortness of breath).
- •Stomach problems, including nausea with or without vomiting.
- •Mild hair loss; hair usually grows back after treatment.
- •Darkening of the skin.
RARE
- •Allergic reactions, such as itching, rash, swelling of the face, lips, tongue, or throat, difficulty swallowing or breathing, or low blood pressure.
- •Breathing difficulties caused by an allergic reaction, inflammation, or lung infection.
- •Fungal, viral, or bacterial infections, which may cause fever, sweating, and a general feeling of illness.
- •Digestive tract problems.
- •Different types of blood cancers (after long-term treatment).
- •Inflammation of the mouth lining (stomatitis).
- •Severe decrease in all blood cells (pancytopenia), causing weakness, bruising, and increased risk of infection.
- •Addison's disease (adrenal glands not working well), causing skin darkening, stomach problems, low blood pressure, and general weakness.
- •Sweating, shaking, and hunger due to low blood sugar.
- •Tingling and numbness (paresthesia).
- •Weakened heart muscle due to structural changes (cardiomyopathy).
- •Shortness of breath (lung inflammation, scarring, and lung infections).
- •Increased liver values (fatigue, pressure in upper right abdomen, yellowing of eyes/skin), hives or itchy rash, skin inflammation, skin redness.
- •Bladder inflammation, causing pain, frequent/urgent urination, with or without bloody urine.
- •General feeling of illness (flu-like symptoms).
- •Pain or swelling at the injection site (if treosulfan solution leaks into surrounding tissue).
- •Blood poisoning (sepsis).
Important Warnings
- Do not use if you are allergic to treosulfan.
- Do not use if you have too few blood cells (severe bone marrow depression).
- Do not breastfeed during treatment.
- You have an increased risk of getting infections, and you should not receive live vaccines.
- Different types of blood cancers can occur after long-term treatment.
Show 4 more warnings
- Your blood counts must be closely monitored and your dose adjusted if you have kidney problems.
- Drink more fluids than usual for up to 24 hours after treatment to prevent bladder inflammation.
- Women of childbearing age must use effective contraception during and for 6 months after treatment.
- If you feel pain at the injection site, tell your doctor or nurse immediately.