Trasylol
Trasylol helps reduce blood loss and the need for blood transfusions during and after heart surgery.
Form
injektio-/infuusioneste, liuos
Strength
10000 KIU/ml
Active Ingredient
Aprotinine
Manufacturer
Nordic Group B.V.
How to Use
Dosage
Before surgery, you will get a small 1 ml test dose. If no allergy, you will receive 100-200 ml over 20-30 minutes, followed by 25-50 ml per hour until the end of the surgery.
Method
The medicine is given slowly into a vein through a catheter (as a drip) while you are lying down.
Important
You will generally not receive more than 700 ml of Trasylol at one time.
Possible Side Effects
COMMON
- •Higher creatinine levels in the blood
RARE
- •Allergic reactions such as difficulty breathing, low blood pressure, itching, rash, hives, nausea, or severe, life-threatening allergic shock
- •Chest pain, heart attack, or fluid buildup around the heart
- •Blood clots in blood vessels, including in the lungs or brain (stroke)
- •Kidney disease, acute kidney failure, or decreased urine output
- •Swelling or inflammation at the injection or infusion site
- •Severe blood clotting disorder that can lead to tissue damage or bleeding
Important Warnings
- Do not use if you are allergic to aprotinin or any other ingredient in this medicine.
- Do not use if you have a positive test for aprotinin-specific antibodies, as this means a higher risk of severe allergic reactions.
- Do not use if you have been treated with Trasylol or suspect you have received it in the last 12 months, and an antibody test cannot be done.
- Tell your doctor if you have kidney problems. Trasylol may only be used if your doctor determines the benefits outweigh the risks.
- You will be closely monitored for allergic reactions, and emergency equipment will be available for severe reactions.