Tramal
Tramal is a pain medicine that belongs to opioids and works in your brain and spinal cord to relieve moderate to severe pain.
Form
kapseli, kova
Strength
50 mg
Active Ingredient
Tramadol hydrochloride
Manufacturer
Orion Corporation
How to Use
Dosage
Adults and children 12 years and older: Take 1 or 2 capsules (50 mg or 100 mg of tramadol hydrochloride).
Method
Swallow capsules whole with enough liquid; do not split or chew. Can be taken with or without food.
Important
Do not take more than 8 capsules (400 mg of tramadol hydrochloride) in one day, unless your doctor tells you otherwise.
Possible Side Effects
COMMON
- •Dizziness
- •Nausea (feeling sick)
- •Headache, drowsiness
- •Tiredness
- •Constipation, dry mouth, vomiting
- •Increased sweating
RARE
- •Pounding heart, fast heart rate, feeling weak or fainting (especially when standing up or exercising).
- •Gagging, stomach discomfort (like pressure or bloating), or diarrhea.
- •Skin reactions like itching or rash.
- •Slow heart rate, increased blood pressure.
- •Strange sensations (like itching, tingling, or numbness), shaking, muscle twitching, problems with coordination, briefly passing out, or speech problems.
- •Seizures (fits), especially with high doses or other seizure-causing medicines.
- •Changes in how much you want to eat.
- •Seeing or hearing things that aren't there (hallucinations), confusion, trouble sleeping, sudden severe confusion (delirium), anxiety, and bad dreams.
- •Mood changes (usually feeling better, sometimes irritable), changes in activity (usually less, sometimes more), and changes in how you think or sense things.
- •Becoming dependent on the medicine with long-term use. Stopping suddenly can cause withdrawal symptoms.
- •Blurred vision, pupils getting larger or smaller.
- •Shortness of breath; breathing becoming slower, especially with high doses or when taken with other medicines that slow brain activity.
- •Asthma getting worse (it's not clear if this is caused by Tramal).
- •Muscle weakness.
- •Trouble or pain when peeing, or peeing less often.
- •Higher levels of liver enzymes (found in blood tests).
- •Low blood sugar.
- •Hiccups.
- •Serotonin syndrome (a serious condition with symptoms like agitation, confusion, fast heart rate, sweating, muscle stiffness, or stomach problems like nausea or diarrhea).
Important Warnings
- Contact a doctor right away if you have signs of a severe allergic reaction, such as swelling of the face, tongue, or throat, trouble swallowing or breathing, or hives.
- Do not take if you have acute poisoning from alcohol, sleeping pills, pain medications, or other medicines that affect your mood or feelings.
- Do not take if you have used certain antidepressants (MAO inhibitors) in the last 14 days.
- Do not take if you have epilepsy that is not well controlled by medicine.
- Do not use for withdrawal treatment from other opioid medicines.
Show 7 more warnings
- Do not take if you have severe liver or kidney problems.
- Do not drink alcohol while taking Tramal, as it can make the medicine's effects stronger.
- Do not use if you are pregnant or breastfeeding.
- This medicine can make you sleepy, dizzy, or blur your vision. Do not drive or use machines if you feel impaired.
- Tramal is not for children under 12 years old.
- This medicine is an opioid and can cause addiction if used for a long time. Talk to your doctor if you are worried about dependence.
- Taking Tramal with some antidepressants can cause a serious condition called serotonin syndrome. Get medical help right away if you have symptoms like confusion, fast heart rate, sweating, or stiff muscles.
Use in Elderly Patients
Category D
Avoid use in older adults. Serotonergic. Prodrug. Genotype affects the response. Reduce the dose in moderately severe and severe renal impairment. Increases the risk of confusion and falling. Need for laxative is often necessary. Consider potential interactions. (updated 18.8.2025)