Tramadol/Paracetamol Krka
Tramadol/Paracetamol Krka is a combination medicine containing tramadol and paracetamol, which work together to relieve moderate to severe pain.
Form
tabletti, kalvopäällysteinen
Strength
37.5 mg / 325 mg
Active Ingredient
Tramadol hydrochloride
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
The usual starting dose for adults and young people over 12 years old is two tablets, unless otherwise prescribed by a doctor.
Method
Take the tablets by mouth. Swallow them whole with enough liquid. Do not break or chew them.
Important
Do not take more than 8 tablets of Tramadol/Paracetamol Krka per day.
Possible Side Effects
COMMON
- •Nausea
- •Dizziness and drowsiness
RARE
- •Vomiting
- •Digestive problems (constipation, gas, diarrhea), stomach pain, dry mouth
- •Itching and increased sweating
- •Headache and shaking
- •Confusion, sleep problems, and mood changes (anxiety, nervousness, feeling 'high')
- •Fast heartbeat or high blood pressure, abnormal heart rhythm
- •Unusual tingling in limbs, ringing in ears, involuntary muscle twitching
- •Depression, nightmares, hallucinations, memory loss
- •Difficulty breathing
- •Difficulty swallowing, blood in stool
- •Skin reactions (hives, rashes)
- •Elevated liver enzyme levels
- •Difficulty or pain when urinating, protein in urine
- •Chills, hot flashes, chest pain
- •Seizures, difficulty with movement, temporary fainting
- •Drug dependence
- •Severe confusion (delirium)
- •Blurred vision, narrowed pupils
- •Speech problems
- •Widened pupils
- •Drug abuse
- •Low blood sugar
- •Hiccups
- •Serotonin syndrome (symptoms like agitation, hallucinations, fever, fast heartbeat, unstable blood pressure, muscle stiffness, twitching, coordination problems, nausea, vomiting, diarrhea)
Important Warnings
- Do not take this medicine if you are allergic to paracetamol, tramadol hydrochloride, or any other ingredient in this medicine.
- Do not take this medicine if you are acutely poisoned by alcohol, sleeping pills, other pain relievers, or medicines affecting your mood or mental state.
- Do not take this medicine if you are using monoamine oxidase (MAO) inhibitors (medicines for depression or Parkinson's disease), or have taken them within 14 days before starting Tramadol/Paracetamol Krka.
- Do not take this medicine if you have severe liver disease.
- Do not take this medicine if you have epilepsy that is not well controlled with your current medication.
Show 7 more warnings
- This medicine contains paracetamol and tramadol. Tell your doctor if you are taking any other medicine containing paracetamol or tramadol to avoid exceeding the maximum daily dose of these substances.
- Tramadol is not recommended for children with breathing problems, as symptoms of tramadol poisoning can be more severe in such children.
- Do not use this medicine during pregnancy or breastfeeding. If you become pregnant, contact your doctor before taking more tablets.
- This medicine may cause drowsiness, which can affect your ability to drive or use machinery safely.
- If you take too much of this medicine, contact a doctor or pharmacist immediately, even if you feel well, as there is a risk of delayed severe liver damage.
- Rarely, a rash, sudden swelling of the face and neck, difficulty breathing, or a drop in blood pressure with fainting may occur, indicating an allergic reaction. If these symptoms occur, stop treatment and contact a doctor immediately; do not take the medicine again.
- Repeated use of this opioid pain medicine can lead to reduced effectiveness (tolerance), abuse, and dependence, which can result in life-threatening overdose. The risk of these side effects increases with higher doses and longer use.
Use in Elderly Patients
Category A
Suitable for older adults. The recommended maximum dose for long-term use is 2 grams per day. Can be used concurrently with warfarin only if INR values are monitored. Consider paracetamol in OTC drugs and combination products. Risk of poisoning with daily doses over 4 grams. (updated 14.4.2024)