Tramadol Hexal

Tramadol Hexal is a pain medicine that helps relieve moderate to severe pain by working on your central nervous system.

Form
kapseli, kova
Strength
100 mg
Active Ingredient
Tramadol hydrochloride
Manufacturer
Hexal A/S

How to Use

Dosage

The usual starting dose is 50–100 mg. For long-term use, take 50–100 mg every 6–8 hours.

Method

Swallow the capsules whole with at least half a glass of water.

Important

Do not take more than 400 mg per day, unless your doctor tells you to.

Possible Side Effects

COMMON
  • Dizziness
  • Nausea
  • Headache
  • Drowsiness
  • Tiredness
  • Constipation
  • Dry mouth
  • Vomiting
  • Sweating
  • Heart and circulation problems (e.g., fast heartbeat, fainting)
  • Gagging
  • Stomach problems (e.g., feeling of pressure, bloating)
  • Diarrhea
  • Skin reactions (e.g., itching, rash)
RARE
  • Allergic reactions (e.g., difficulty breathing, wheezing, swelling of skin) and shock (sudden collapse of circulation)
  • Slow heart rate
  • High blood pressure
  • Unusual sensations (e.g., itching, tingling, numbness)
  • Tremors
  • Seizures
  • Muscle twitching
  • Coordination problems with movements
  • Fainting
  • Speech problems
  • Changes in appetite
  • Hallucinations
  • Confusion
  • Sleep disturbances
  • Anxiety
  • Nightmares
  • Drug dependence
  • Blurred vision
  • Pupil changes (small or large pupils)
  • Slow breathing, shortness of breath
  • Muscle weakness
  • Difficulty or painful urination, reduced urine amount
  • Increased liver enzyme levels
  • Low blood sugar
  • Sleep apnea (breathing stops during sleep)
  • Hiccups

Important Warnings

  • Do not use if you are allergic to tramadol or any other ingredient in this medicine.
  • Do not use if you are poisoned by alcohol, sleeping pills, other pain medicines, or mood-affecting medicines.
  • Do not use if you have taken MAO inhibitors (medicines for depression) in the last 14 days.
  • Do not use if you have epilepsy that is not controlled by medicine.
  • Do not use as a replacement treatment for drug addiction.
Show 15 more warnings
  • Talk to your doctor if you suspect you are dependent on other opioid pain medicines.
  • Talk to your doctor if you are sensitive to opiates.
  • Talk to your doctor if you have confusion or feel dizzy.
  • Talk to your doctor if you are in shock (which can cause cold sweats).
  • Talk to your doctor if you have increased pressure in your brain (e.g., after a head injury or brain disease).
  • Talk to your doctor if you have breathing difficulties.
  • Talk to your doctor if you have epilepsy or have had seizures, as the risk of seizures may increase.
  • Talk to your doctor if you have liver or kidney disease.
  • Talk to your doctor if you have depression and use antidepressants, as some can interact with tramadol.
  • Stop taking this medicine and see a doctor immediately if you experience slow or shallow breathing, confusion, sleepiness, small pupils, nausea, vomiting, constipation, or loss of appetite, as these could be signs of serious side effects.
  • Contact your doctor if you or someone else notices breathing pauses during sleep, waking up at night due to shortness of breath, difficulty staying asleep, or severe daytime sleepiness.
  • Immediately contact a doctor if you experience severe tiredness, loss of appetite, severe stomach pain, nausea, vomiting, or low blood pressure, as these may indicate adrenal insufficiency and you might need hormone supplements.
  • Avoid alcohol while taking Tramadol Hexal, as it can make the medicine's effects stronger.
  • Do not drive or use machines if you feel tired, dizzy, or have blurred vision, as your reaction time may be slower.
  • Seek immediate medical attention if you experience swelling of the face, tongue, and/or throat, difficulty swallowing, or hives with breathing problems.

Use in Elderly Patients

Category D

Avoid use in older adults. Serotonergic. Prodrug. Genotype affects the response. Reduce the dose in moderately severe and severe renal impairment. Increases the risk of confusion and falling. Need for laxative is often necessary. Consider potential interactions. (updated 18.8.2025)