Tradolan Retard

Tradolan Retard is a strong opioid pain reliever used to treat moderate to severe pain by affecting nerve cells in the brain and spinal cord.

Form
depottabletti
Strength
150 mg
Active Ingredient
Tramadol hydrochloride
Manufacturer
G.L. Pharma GmbH

How to Use

Dosage

Usually one 100 mg tablet twice a day (morning and evening). Your doctor may adjust the dose if needed.

Method

Swallow the tablets whole with plenty of liquid. Do not chew them. You can take them with or without food.

Important

Do not take more than 400 mg total per day, unless your doctor tells you to.

Possible Side Effects

COMMON
  • Dizziness
  • Nausea (feeling sick)
  • Headache
  • Drowsiness (feeling sleepy)
  • Tiredness
  • Vomiting (being sick)
  • Constipation (difficulty passing stool)
  • Dry mouth
  • Sweating
RARE
  • Heart effects (like a pounding or fast heartbeat). These are more common when standing up or during physical activity.
  • Stomach discomfort (like a feeling of pressure or bloating), diarrhea.
  • Skin reactions (like itching, rash).
  • Allergic reactions (like trouble breathing, wheezing, skin swelling) and shock (sudden collapse of blood circulation).
  • Slow heart rate.
  • Increased blood pressure.
  • Unusual feelings (like itching, tingling, numbness), shaking, seizures, muscle jerks, problems with coordination, temporary fainting, speech problems.
  • Changes in appetite.
  • Seeing or hearing things that aren't there (hallucinations), confusion, sleep problems, delirium, anxiety, and nightmares.
  • Drug dependence.
  • Blurred vision, pupils getting bigger (mydriasis) or smaller (miosis).
  • Slowed breathing, shortness of breath.
  • Muscle weakness.
  • Difficulty or pain when urinating, producing less urine.
  • Elevated liver enzymes (shown in blood tests).
  • Low blood sugar.
  • Hiccups.
  • Serotonin syndrome (can include changes in mood, fast heartbeat, changes in blood pressure, stiff muscles, problems with coordination, and stomach/gut issues).

Important Warnings

  • Do not take if you are allergic to tramadol or any other ingredient in this medicine.
  • Do not take if you have recently taken alcohol, sleeping pills, other strong pain relievers, or certain medicines for mental health.
  • Do not take if you are taking or have taken MAO inhibitors (certain medicines for depression) in the last 14 days.
  • Do not take if your epilepsy is not well controlled with your current treatment.
  • Not for use to help with opioid withdrawal.
Show 9 more warnings
  • Be careful if you have or have had an addiction to other strong pain medicines.
  • Be careful if you feel dizzy or faint, or are in shock (cold sweat can be a sign).
  • Be careful if you have increased pressure in your head (e.g., from a head injury) or breathing problems.
  • Be careful if you have liver or kidney disease.
  • Be careful if you have depression and take antidepressants, as they can interact with this medicine.
  • This medicine can cause breathing problems while you sleep. Tell your doctor if you pause breathing during sleep, wake up short of breath, have trouble sleeping, or feel very tired during the day.
  • Not recommended during pregnancy.
  • Not recommended for more than a single dose while breastfeeding, or stop breastfeeding if taken more often.
  • This medicine can make you feel sleepy, dizzy, or have blurred vision. Do not drive or use machines if you feel this way.

Use in Elderly Patients

Category D

Avoid use in older adults. Serotonergic. Prodrug. Genotype affects the response. Reduce the dose in moderately severe and severe renal impairment. Increases the risk of confusion and falling. Need for laxative is often necessary. Consider potential interactions. (updated 18.8.2025)