Topogyne
Topogyne tablets contain misoprostol, which helps to start uterine contractions and soften the cervix, and are used for abortion.
Form
tabletti
Strength
400 mikrog
Active Ingredient
Misoprostol
Manufacturer
Exelgyn
How to Use
Dosage
One tablet.
Method
Swallow the tablet whole with a glass of water. For medical abortion, take Topogyne 36–48 hours after taking 600 mg of mifepristone. For surgical abortion, take the tablet 3–4 hours before the procedure.
Important
A single tablet is taken as one dose, as directed by your doctor.
Possible Side Effects
COMMON
- •Uterine contractions or cramps
- •Diarrhea
- •Nausea or vomiting
- •Bleeding from the uterus
- •Heavy vaginal bleeding
- •Abdominal pain
- •Mild to moderate stomach or intestinal cramps
- •Uterine infection (endometritis or pelvic inflammation)
- •Congenital malformations (fetal malformations)
RARE
- •Fever
- •Fetal death
- •Headache, dizziness, general malaise or fatigue
- •Hives and serious skin diseases (e.g., severe itchy red patches, blisters or sores)
- •Uterine rupture (tearing of the uterus)
- •Local swelling of face and/or throat, possibly with hives
- •Chills
- •Back pain
- •Severe allergic reaction
- •Heart and blood vessel problems (e.g., chest pain, breathing difficulties, confusion, or irregular heartbeat, which can lead to cardiac arrest)
- •Severe or fatal toxic or septic shock (symptoms like fever, muscle pain, rapid heart rate, dizziness, diarrhea, vomiting, or weakness)
Important Warnings
- Do not take if you are allergic to misoprostol, prostaglandins, or any other ingredient in this medicine.
- Do not take if your pregnancy has not been confirmed by ultrasound or tests.
- Do not take if your doctor suspects an ectopic pregnancy (pregnancy outside the womb).
- Do not take if you cannot take mifepristone (when Topogyne is used with it).
- Do not take for medical abortion if it's been more than 49 days (7 weeks) since the first day of your last period.
Show 8 more warnings
- Talk to your doctor if you have liver or kidney disease.
- Talk to your doctor if you have anemia or are malnourished.
- Talk to your doctor if you have cardiovascular (heart or blood vessel) disease or an increased risk for it (e.g., over 35, smoker, high blood pressure, high cholesterol, diabetes).
- Talk to your doctor if you have a blood clotting disorder.
- Talk to your doctor if you have had a C-section or other uterine surgery.
- If you have an IUD (intrauterine device), it must be removed before taking this medicine.
- Do not use this medicine if the blister packaging is damaged or if the tablet has not been stored in its packaging.
- Do not travel far from the treatment center until after your follow-up appointment.