Tisamid
Tisamid is a medicine used to treat tuberculosis by fighting the bacteria that cause it and preventing them from becoming resistant to treatment.
Form
tabletti
Strength
500 mg
Active Ingredient
Pyrazinamide
Manufacturer
Orion Corporation
How to Use
Dosage
Your doctor will decide your dose, usually 20-30 mg per kg of body weight daily or 30-40 mg per kg of body weight three times a week.
Method
Take the tablets on an empty stomach, exactly as your doctor has told you.
Important
Maximum 2.5 grams daily, or 3 grams three times a week, depending on your prescribed dose.
Possible Side Effects
COMMON
- •High levels of uric acid in your blood (which can cause gout)
- •Feeling sick (nausea), not wanting to eat, vomiting
- •Increased liver enzyme levels
- •Gout, joint pain
- •Tuberculosis symptoms returning or getting worse (e.g., cough, fever, tiredness, shortness of breath, headache, not wanting to eat, weight loss, weakness)
RARE
- •Acute porphyria (a rare problem with your body's metabolism)
- •Liver damage or failure, liver inflammation (hepatitis), yellowing of the skin or eyes (jaundice), enlarged liver
- •Low number of blood platelets (thrombocytopenia), a specific type of anemia (sideroblastic anemia)
- •Skin rashes, sensitivity to sunlight, severe swelling of skin or mucous membranes, hives, itching, or a severe allergic reaction with rash, fever, and organ problems (DRESS syndrome)
- •Kidney inflammation, problems with urination
- •Fever caused by the medicine
- •Lack of vitamin B3 (pellagra), which can cause rash, diarrhea, and memory problems
- •Enlarged spleen
- •Seizures, headache, dizziness
- •Worsening of stomach ulcers
Important Warnings
- Do not take if you are allergic to pyrazinamide or any other ingredient in this medicine.
- Do not take if you have severe liver disease (with jaundice) or porphyria (a rare metabolic disorder).
- Talk to your doctor before taking if you have gout, liver damage, kidney problems, or diabetes.
- Do not drink alcohol during treatment, as it can increase the risk of liver damage.
- Avoid strong sunlight, as this medicine can make you sensitive to the sun.
Show 1 more warnings
- See your doctor right away if your tuberculosis symptoms return or get worse during treatment.