Thymoglobuline
This medicine helps your body accept transplanted organs and can treat other unwanted immune reactions by weakening your immune system.
Form
infuusiokuiva-aine, liuosta varten
Strength
5 mg/ml
Active Ingredient
Anti-human-T-lymphocyte immunoglobulin from rabbit
Manufacturer
Sanofi B.V.
How to Use
Dosage
Your dose depends on your weight, the condition being treated, and other medicines you might be taking; for example, for kidney transplants, it's typically 1.25-1.5 mg per kg daily.
Method
A doctor or nurse will give you this medicine in the hospital through a plastic tube (catheter) directly into your bloodstream (intravenous infusion) over at least 4 hours, and the first dose might take longer.
Important
The maximum daily dose depends on your weight and the condition being treated, typically up to 1.5 mg per kg of body weight.
Possible Side Effects
COMMON
- •Low white blood cell count
- •Low platelet count
- •Fever
- •Infection
- •Low red blood cell count (anemia)
- •Diarrhea
- •Difficulty swallowing
- •Nausea
- •Vomiting
- •Chills
- •Rash
- •Itching
- •Hives
- •Joint pain
- •Kidney problems
- •Swollen lymph nodes
- •Muscle pain
- •Certain types of cancer
- •Shortness of breath
- •Low blood pressure
- •Increased liver enzymes
RARE
- •Liver damage
Important Warnings
- Do not use if you have an active infection, as this medicine weakens your immune system and makes it harder to fight infections.
- Do not use if you are allergic to rabbit proteins or any other ingredient in this medicine.
- This medicine must always be given under close medical supervision in a hospital.
- Your doctor will regularly check your blood and health during treatment, as this medicine can affect your blood cells and other organs.
- Tell your doctor if you have ever had an allergic reaction to animals or other medicines.
Show 3 more warnings
- Avoid vaccinations during or shortly after treatment without first talking to your doctor, as vaccines may not work or could cause side effects.
- If you are pregnant, think you might be pregnant, or are breastfeeding, talk to your doctor before using this medicine.
- Do not drive or operate machinery if you feel unwell, tired, or dizzy, as this medicine can affect your ability to do so.