Temozolomid ratiopharm
Temozolomid ratiopharm is a medicine containing temozolomide, used to treat certain brain tumors.
Form
kapseli, kova
Strength
180 mg
Active Ingredient
Temozolomide
Manufacturer
ratiopharm GmbH
How to Use
Dosage
Your doctor will determine the correct dose based on your body size and condition.
Method
Take the capsules whole with a glass of water on an empty stomach, preferably one hour before breakfast. Do not open, crush, or chew the capsules.
Important
Never take more than your doctor prescribes. Taking too much can be dangerous.
Possible Side Effects
COMMON
- •loss of appetite
- •speech problems
- •headache
- •vomiting
- •nausea
- •diarrhea
- •constipation
- •rash
- •hair loss
- •fatigue
- •infections
- •mouth infections
- •decreased blood cell counts (neutrophils, lymphocytes, and platelets)
- •allergic reactions
- •high blood sugar
- •memory impairment
- •depression
- •anxiety
- •confusion
- •difficulty falling asleep or staying asleep
- •impaired coordination
- •balance problems
- •concentration difficulties
- •changes in mental state or alertness
- •forgetfulness
- •dizziness
- •impaired sense of touch
- •tingling
- •tremor
- •taste changes
- •partial vision loss
- •abnormal vision
- •double vision
- •sore eyes
- •deafness
- •ringing in ears
- •ear pain
- •pulmonary embolism
- •blood clots in legs
- •high blood pressure
- •pneumonia
- •shortness of breath
- •bronchitis
- •cough
- •sinusitis
- •abdominal pain
- •stomach discomfort
- •heartburn
- •difficulty swallowing
- •dry skin
- •itching
- •muscle damage
- •muscle weakness
- •muscle aches and pains
- •joint pain
- •back pain
- •frequent urination
- •difficulty holding urine
- •fever
- •flu-like symptoms
- •pain
- •malaise
- •common cold or flu
- •fluid retention
- •swollen legs
- •elevated liver enzymes
- •weight loss
- •weight gain
- •radiation damage
RARE
- •brain infections caused by herpes virus (including fatal cases)
- •wound infections
- •new or reactivated cytomegalovirus infections
- •reactivated Hepatitis B virus infections
- •development of other cancers (incl. leukemia)
- •decreased counts of certain blood cells (pancytopenia, red blood cell deficiency, white blood cell deficiency)
- •red spots under the skin
- •diabetes insipidus (symptoms: frequent urination and thirst), low blood potassium
- •mood swings
- •hallucinations
- •partial paralysis
- •changes in sense of smell
- •impaired hearing
- •middle ear infection
- •palpitations (feeling your heart beat)
- •hot flashes
- •swollen abdomen
- •difficulty controlling bowel movements
- •hemorrhoids
- •dry mouth
- •liver inflammation and damage (incl. fatal liver failure)
- •bile flow problems (cholestasis)
- •increased bilirubin levels
- •blisters on body or in mouth
- •flaky skin
- •rash
- •painful skin redness
- •severe rash with skin swelling (incl. on palms and soles)
- •sun sensitivity
- •hives (urticaria)
- •increased sweating
- •skin color changes
- •difficulty urinating
- •vaginal bleeding
- •vaginal irritation
- •missed or heavy periods
- •breast pain
- •sexual inability (impotence)
- •chills
- •facial swelling
- •tongue discoloration
- •thirst
- •dental problems
- •dry eyes
Important Warnings
- Do not use if you are allergic to temozolomide, other ingredients in this medicine, or if you've had an allergic reaction to the cancer medicine dacarbazine.
- Your doctor will check your blood counts before treatment, as this medicine can affect your blood cells.
- You will be monitored for a serious lung infection, and if you are receiving radiation therapy, your doctor may prescribe medication to prevent it.
- Tell your doctor if you have had Hepatitis B, as this medicine can reactivate the virus.
- If you experience nausea or vomiting, tell your doctor. Do not take a second dose on the same day if you vomit after taking your dose.
Show 5 more warnings
- Contact your doctor immediately if you develop a fever or signs of infection.
- Patients over 70 may be more prone to infections, bruising, and bleeding.
- If you have liver or kidney problems, your doctor may need to adjust your dose.
- This medicine can make you feel tired or sleepy. Do not drive or operate machinery if you feel tired.
- Do not use this medicine if you are pregnant or breastfeeding. Use reliable contraception during treatment and for a certain period after. Discuss fertility with your doctor.