Temozolomid ratiopharm
Temozolomid ratiopharm contains temozolomide and is used to treat certain types of brain tumors.
Form
kapseli, kova
Strength
20 mg
Active Ingredient
Temozolomide
Manufacturer
ratiopharm GmbH
How to Use
Dosage
Your doctor will determine the correct dose for you based on your body size and condition.
Method
Take the capsules once a day, preferably at the same time and on an empty stomach, at least one hour before breakfast. Swallow the capsule(s) whole with water; do not open, crush, or chew them. If a capsule breaks, avoid powder contact with skin or eyes, and rinse immediately with water if it occurs.
Important
Your doctor will prescribe your maximum daily dose, which may change during your treatment cycle.
Possible Side Effects
COMMON
- •Loss of appetite
- •Speech problems
- •Headache
- •Vomiting, nausea, diarrhea, constipation
- •Rash, hair loss
- •Tiredness
- •Infections, mouth infections
- •Decrease in blood cell counts (neutrophils, lymphocytes, and platelets)
- •Allergic reactions
- •Increased blood sugar
- •Memory problems, depression, anxiety, confusion, sleep disorders
- •Impaired coordination, balance problems, difficulty concentrating
- •Dizziness, tingling, tremor, altered taste
- •Vision problems (partial vision loss, double vision, sore eyes)
- •Deafness, ringing in ears, ear pain
- •Blood clots (in lungs or legs), high blood pressure
- •Pneumonia, shortness of breath, cough, sinusitis
- •Abdominal pain, heartburn, difficulty swallowing, dry mouth
- •Dry skin, itching
- •Muscle aches, muscle weakness, joint pain, back pain
- •Frequent urination, difficulty holding urine
- •Pain, malaise, cold or flu-like symptoms
- •Fluid retention, swollen legs
- •Increased liver enzymes
- •Weight loss or gain
- •Radiation injury
RARE
- •Brain infections caused by herpesvirus
- •Wound infections
- •Cytomegalovirus or Hepatitis B virus infections
- •Development of other cancers (including leukemia)
- •Severe decrease in blood cell counts (pancytopenia, anemia)
- •Red spots under the skin
- •Diabetes insipidus (severe thirst and frequent urination), low potassium
- •Mood swings, hallucinations
- •Partial paralysis, altered sense of smell
- •Impaired hearing, middle ear infections
- •Heart palpitations, hot flashes
- •Swollen abdomen, difficulty controlling bowel movements, hemorrhoids
- •Hepatitis, liver damage, bile flow problems, increased bilirubin
- •Blisters on body or in mouth, flaky skin, severe rashes with skin swelling
- •Skin sensitivity to sunlight, hives, increased sweating, changes in skin color
- •Difficulty urinating
- •Vaginal bleeding, irritation, menstrual irregularities, breast pain, impotence
- •Chills, facial swelling, tongue discoloration, thirst, dental problems, dry eyes
Important Warnings
- Do not use if you are allergic to temozolomide, dacarbazine, or any other ingredients.
- This medicine can affect your blood cells; your doctor will check your blood counts regularly.
- Tell your doctor immediately if you have fever, signs of infection, or unusual bleeding.
- May cause tiredness or drowsiness; do not drive or operate machinery until you know how the medicine affects you.
- Not recommended for pregnant or breastfeeding women; men face a risk of permanent infertility, so use contraception.