Tavanic
Tavanic tablets contain levofloxacin, an antibiotic that fights bacteria causing infections in your body.
Form
tabletti, kalvopäällysteinen
Strength
500 mg
Active Ingredient
Levofloxacin hemihydrate
Manufacturer
Sanofi Oy
How to Use
Dosage
Your doctor will tell you how many Tavanic tablets to take; typically it is one 500 mg tablet once a day.
Method
Take the tablets by mouth, swallowing them whole with water. You can take them with or without food.
Important
Do not exceed your doctor's prescribed dose, typically no more than two 500 mg tablets per day.
Possible Side Effects
COMMON
- •Sleep problems
- •Headache, dizziness
- •Feeling sick (nausea, vomiting) and diarrhea
- •Increased levels of certain liver enzymes in blood tests
- •Changes in the number of other bacteria or fungi, such as a Candida yeast infection that may require treatment
- •Changes in white blood cell counts seen in blood tests (leukopenia, eosinophilia)
- •Feeling anxious, confused, nervous, sleepy, shaking (tremor), or having a spinning sensation (vertigo)
- •Shortness of breath
- •Changes in taste, loss of appetite, indigestion, stomach pain, bloating (gas), or constipation
- •Itching and skin rash, severe itching or hives (urticaria), excessive sweating
- •Joint or muscle pain
- •Unusual blood test results due to liver (increased bilirubin) or kidney (increased creatinine) problems
- •General weakness
RARE
- •Allergic reaction with symptoms like rash, difficulty swallowing or breathing, swelling of lips, face, throat, or tongue.
- •Watery diarrhea, which may be bloody, with stomach cramps and high fever; signs of severe bowel problems.
- •Pain and inflammation in your tendons or ligaments, especially the Achilles tendon, which can lead to rupture.
- •Seizures (convulsions).
- •Seeing or hearing things that are not real (hallucinations, paranoia).
- •Feeling depressed, having mental problems, feeling restless (agitation), abnormal dreams or nightmares.
- •Severe skin rashes including Stevens-Johnson syndrome, toxic epidermal necrolysis, DRESS syndrome, and AGEP, with red, target-like spots or round patches, often with blisters, peeling skin, and sores in the mouth, throat, nose, genitals, and eyes, often preceded by fever and flu-like symptoms.
- •Low blood sugar (hypoglycemia) or very low blood sugar leading to coma, especially important for diabetics.
- •Burning sensation, tingling, pain, or numbness, which can be signs of nerve damage (neuropathy).
- •Loss of appetite, yellow skin and eyes, dark urine, itching, or tender stomach (liver problems, possibly leading to liver failure).
- •Changes in thoughts or mood (psychotic reactions), including risk of suicidal thoughts and attempts, and panic attacks.
- •Nausea, general unwellness, stomach problems, stomach pain or vomiting; these can be symptoms of acute pancreatitis (inflammation of the pancreas).
- •Easy bruising or bleeding due to a decrease in blood platelets (thrombocytopenia).
- •Changes in how your kidneys work and temporary kidney failure, possibly due to an allergic reaction in the kidneys (interstitial nephritis).
- •Fever.
- •Unusual fast heartbeat (tachycardia) or low blood pressure (hypotension).
- •Decreased red blood cells (anemia), causing pale or yellow skin, or a decrease in all blood cells (pancytopenia).
- •Bone marrow stops making new blood cells, causing tiredness, weaker immune system, and uncontrolled bleeding (bone marrow failure).
- •Persistent fever, sore throat, and general unwellness, possibly due to a decrease in white blood cells (agranulocytosis).
- •Lack of circulation (similar to anaphylactic shock).
- •Increased blood sugar (hyperglycemia), important for diabetics.
- •Changes in how things smell, loss of smell or taste.
- •Strong feeling of excitement, elation, agitation, or enthusiasm (mania).
- •Problems with movement or walking (dyskinesia, extrapyramidal disorders).
- •Fainting (syncope), temporary loss of consciousness or posture.
- •Decreased vision, temporary loss of vision, or other eye problems like inflammation.
- •Decreased or lost hearing.
- •Abnormally fast heart rate, life-threatening irregular heartbeat including cardiac arrest, or changes in heart rhythm (prolonged QT interval seen on ECG).
- •Difficulty breathing or wheezing (bronchospasm).
- •Liver inflammation (hepatitis).
- •Increased skin sensitivity to sunlight and UV light (photosensitivity), or darker skin areas (hyperpigmentation).
- •Blood vessel inflammation due to an allergic reaction (vasculitis).
- •Mouth inflammation (stomatitis).
- •Muscle ruptures and muscle damage (rhabdomyolysis).
- •Redness and swelling in joints (arthritis).
- •Pain, including back, chest, and limb pain.
- •Sudden involuntary jerking, muscle twitching or contractions (myoclonus).
- •Persistent headache with or without blurred vision (idiopathic intracranial hypertension).
- •Widening or tearing of the aorta (main blood vessel), which can be life-threatening, and heart valve leakage.
Important Warnings
- Do not take if you are allergic to levofloxacin, other quinolone antibiotics, or any other ingredients in this medicine.
- Do not take if you have ever had epilepsy (seizures).
- Do not take if you have ever had tendon problems (inflammation or rupture) linked to quinolone antibiotics.
- This medicine should not be given to children or growing adolescents.
- Do not use if you are pregnant, might become pregnant, think you might be pregnant, or if you are breastfeeding.
Show 6 more warnings
- If you develop a severe rash or other serious skin reactions (e.g., blisters, peeling skin), stop using the medicine and contact your doctor immediately.
- Seek immediate emergency care if you feel sudden severe pain in your stomach, chest, or back, as this could be a sign of a widened or torn aorta (main blood vessel).
- If you experience symptoms of nerve damage, such as pain, burning, tingling, numbness, and/or weakness, stop using the medicine and tell your doctor.
- Avoid direct sunlight during treatment and for 2 days after stopping. Use high-SPF sunscreen, a hat, and clothes to protect your skin.
- Do not take Tavanic with iron tablets, zinc supplements, antacids, didanosine, or sucralfate. Take these other medicines at least 2 hours before or after Tavanic.
- Never stop treatment early, even if you feel better, as this can lead to the infection returning or becoming resistant.
Use in Elderly Patients
Category D
Avoid use in older adults. Risk of QT prolongation. Reduce the dose and/or increase the dosing interval in moderately severe renal impairment. Calcium, iron, zinc, magnesium and aluminium reduce absorption. Increases the risk of tendinitis and aortic injury and valvular heart disease. Consider central nervous system adverse effects, especially lowered seizure threshold and confusion. (updated 4.12.2023)