Targiniq
Targiniq is a prolonged-release tablet that slowly releases its active ingredients over 12 hours to help with severe pain or restless legs syndrome.
Form
depottabletti
Strength
40 mg / 20 mg
Active Ingredient
Oxycodone hydrochloride
Manufacturer
Mundipharma Oy
How to Use
Dosage
For pain, the usual starting dose is one 10 mg/5 mg tablet every 12 hours. For restless legs syndrome, the usual starting dose is one 5 mg/2.5 mg tablet every 12 hours.
Method
Swallow the tablets whole with about half a glass of water. Do not break, chew, or crush them. Take them every 12 hours, at the same times each day, with or without food.
Important
For pain, the maximum daily dose of Targiniq is 160 mg oxycodone hydrochloride and 80 mg naloxone hydrochloride. For restless legs syndrome, the maximum daily dose is 60 mg oxycodone hydrochloride and 30 mg naloxone hydrochloride.
Possible Side Effects
COMMON
- •Abdominal pain
- •Constipation
- •Diarrhea
- •Nausea
- •Vomiting
- •Dry mouth
- •Indigestion
- •Flatulence
- •Decreased appetite
- •Dizziness
- •Headache
- •Drowsiness
- •Fatigue or exhaustion
- •Itching
- •Sweating
- •Skin reactions or rash
- •Hot flashes
- •Sleep difficulties
- •Unusual weakness
RARE
- •Abdominal swelling
- •Palpitations (fast or strong heartbeat)
- •Runny nose
- •Anxiety
- •Confusion
- •Depression
- •Nervousness
- •Restlessness
- •Tremor or shaking
- •Difficulty concentrating
- •Speech problems
- •Breathing difficulties
- •Chills
- •Increased liver enzymes (seen in blood tests)
- •Decreased sex drive
- •Increased heart rate
- •Drug dependence
- •Tooth changes
- •Weight gain
- •Yawning
- •Tingling in hands or feet
- •Swelling of hands, ankles, or feet
- •Accidental injuries
- •Increased urination frequency
- •Muscle cramps
- •Muscle twitching
- •Muscle pain
- •Impaired vision
- •Seizures (fits), especially if you have epilepsy or are at risk of seizures
- •Withdrawal symptoms (e.g., agitation)
- •Decreased blood pressure
- •Increased blood pressure
- •Chest pain or tightness
- •General malaise
- •Weight loss
- •Gallstone attack (biliary colic)
Important Warnings
- Do not take if you are allergic to oxycodone, naloxone, or other ingredients in this medicine.
- This medicine is an opioid and can cause addiction; use exactly as prescribed by your doctor.
- Do not crush, chew, or break the tablets as this can release a dangerous amount of medicine at once.
- Combining this medicine with alcohol or sedatives can make you very sleepy, cause severe breathing problems, or lead to coma.
- Do not use during pregnancy or if you are breastfeeding.
Show 2 more warnings
- This medicine can make you sleepy and affect your ability to drive or operate machines.
- Tell your doctor if you have severe lung problems (like slow, shallow breathing), severe liver problems, or a bowel blockage not caused by opioids.