This medicine is a long-acting painkiller that also helps prevent constipation.
Take one 10 mg/5 mg tablet every 12 hours. Your doctor will tell you the exact dose.
Swallow the tablet whole with a glass of water, with or without food. Do not break, crush, or chew the tablet. Take it at the same times each day.
Do not take more than 160 mg of oxycodone and 80 mg of naloxone in one day.
Suitable for older adults, with specific precautions. Sedative. Reduce the dose already in mild renal impairment. Increases the risk of confusion and falling. Need for laxative is often necessary. Consider potential interactions. Avoid grapefruit. (updated 24.3.2025)